LRRIQ1

Description		leucine rich repeats and IQ motif containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Microtubule Cytoskeleton
	Molecular Function
	Biological Process	Apoptotic Process Single Fertilization Regulation Of Signal Transduction Gene Expression Ectopic Germ Cell Programmed Cell Death
Pathways
Drugs
Diseases
GWAS		Bone mineral density (Ward's triangle area) ( 27397699) Brain morphology (MOSTest) ( 32665545) Monobrow ( 27182965) Optic disc size ( 31809533)
Interacting Genes		2 interacting genes: BCL2L2 EMILIN1
Entrez ID		84125
HPRD ID		09952
Ensembl ID		ENSG00000133640
Uniprot IDs		A0A140VJN5 Q96JM4
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Process Sertoli Cell Proliferation Bcl-2 Family Protein Complex Integrin Binding Involved In Cell-matrix Adhesion Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway EMILIN Complex Positive Regulation Of Defense Response To Bacterium Regulation Of Collagen Fibril Organization Integrin Alpha4-beta1 Complex Positive Regulation Of Platelet Aggregation Positive Regulation Of Extracellular Matrix Assembly Extracellular Matrix Constituent Conferring Elasticity Elastic Fiber Assembly Negative Regulation Of Collagen Fibril Organization Negative Regulation Of Collagen Biosynthetic Process Regulation Of Defense Response To Bacterium Negative Regulation Of Macrophage Migration Negative Regulation Of Cellular Response To Vascular Endothelial Growth Factor Stimulus Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Homotypic Cell-cell Adhesion Release Of Cytochrome C From Mitochondria Disordered Domain Specific Binding Positive Regulation Of Extracellular Matrix Organization Positive Regulation Of Coagulation Regulation Of Extracellular Matrix Assembly Negative Regulation Of Extracellular Matrix Organization Regulation Of Platelet Aggregation Negative Regulation Of SMAD Protein Signal Transduction Positive Regulation Of Blood Coagulation Cell Adhesion Mediated By Integrin Extracellular Matrix Assembly Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Aortic Valve Morphogenesis Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Negative Regulation Of Mononuclear Cell Migration Regulation Of Collagen Biosynthetic Process Channel Activity Regulation Of Collagen Metabolic Process Regulation Of Macrophage Migration Negative Regulation Of Leukocyte Migration Regulation Of Platelet Activation Heart Valve Morphogenesis Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Apoptotic Mitochondrial Changes Positive Regulation Of Wound Healing Negative Regulation Of ERK1 And ERK2 Cascade
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