USP44

Description		ubiquitin specific peptidase 44
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Mitotic Spindle
	Molecular Function	Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding Deubiquitinase Activity
	Biological Process	Immune System Process Nucleotide-excision Repair Proteolysis Chromosome Segregation Regulation Of Cell Cycle Process Protein Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulatory T Cell Differentiation Innate Immune Response Negative Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Mitotic Metaphase/anaphase Transition Cell Division Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Antiviral Innate Immune Response Negative Regulation Of Ubiquitin Protein Ligase Activity
Pathways		Ub-specific processing proteases
Drugs
Diseases
GWAS		Brain volume in infants (white matter) ( 28763065) Breast size ( 27182965) C-reactive protein levels ( 30388399) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Response to anti-depressant treatment in major depressive disorder ( 22041458) Type 2 diabetes ( 30297969)
Interacting Genes		1 interacting genes: H2BC1
Entrez ID		84101
HPRD ID		15636
Ensembl ID		ENSG00000136014
Uniprot IDs		F8VRI7 Q9H0E7
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleosome Disassembly Protein-DNA Complex Disassembly Sperm DNA Condensation Female Germ Cell Nucleus Plasminogen Activation Zymogen Activation Nucleosome Histone Binding Nucleosome Assembly Protein-containing Complex Disassembly Protein-DNA Complex Assembly Protein Processing Chromosome, Telomeric Region Mononuclear Cell Migration Nucleosome Organization Structural Constituent Of Chromatin Leukocyte Migration Protein Maturation Protein Heterodimerization Activity Chromosome Organization
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