KLF16

Description		KLF transcription factor 16
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II G Protein-coupled Dopamine Receptor Signaling Pathway
Pathways		TGFBR3 expression
Drugs
Diseases
GWAS		Adult body size ( 32376654) Diverticular disease ( 30177863) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil count ( 32888494) Red blood cell count ( 32888494) Reticulocyte fraction of red cells ( 32888494) White blood cell count ( 32888494)
Interacting Genes		5 interacting genes: HDAC7 NFIA NFIB NFIC SIN3A
Entrez ID		83855
HPRD ID		12090
Ensembl ID		ENSG00000129911
Uniprot IDs		Q9BXK1
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Replication Glial Cell Fate Specification Exit From Mitosis DNA Metabolic Process Generation Of Neurons Neuron Fate Specification Glial Cell Proliferation Regulation Of Transcription By RNA Polymerase II Transcription Regulator Inhibitor Activity Negative Regulation Of Transcription By RNA Polymerase II Histone Deacetylase Complex Chromatin Regulation Of DNA-templated Transcription Chromatin Binding Retina Development In Camera-type Eye Regulation Of RNA Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Cell Fate Specification Negative Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Lung Ciliated Cell Differentiation Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Response To Tert-butyl Hydroperoxide Response To Methylglyoxal Neural Precursor Cell Proliferation Regulation Of RNA Metabolic Process Neurogenesis Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity Double-stranded DNA Binding Cell Differentiation Involved In Salivary Gland Development Negative Regulation Of Mesenchymal Cell Proliferation Involved In Lung Development Nucleoplasm Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Nucleic Acid Metabolic Process Principal Sensory Nucleus Of Trigeminal Nerve Development Fibrillar Center DNA Binding DNA-binding Transcription Factor Binding Club Cell Differentiation Negative Regulation Of Macromolecule Biosynthetic Process Response To Wounding Salivary Gland Cavitation Negative Regulation Of Biosynthetic Process Transcription Corepressor Activity Regulation Of Gene Expression Negative Regulation Of Developmental Process
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