USP26

Description		ubiquitin specific peptidase 26
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Cilium Motile Cilium Sperm Flagellum Cell Projection
	Molecular Function	Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity Deubiquitinase Activity K48-linked Deubiquitinase Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Proteolysis Spermatogenesis Protein Deubiquitination Regulation Of Protein Stability Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Androgen Receptor Signaling Pathway
Pathways		Ub-specific processing proteases
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: CDKN2A CFTR TAFAZZIN
Entrez ID		83844
HPRD ID		02255
Ensembl ID		ENSG00000134588
Uniprot IDs		Q9BXU7
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Macrophage Apoptotic Process Mitochondrial Depolarization Oncogene-induced Cell Senescence Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Negative Regulation Of Protein Neddylation Ubiquitin-protein Transferase Inhibitor Activity Negative Regulation Of Immature T Cell Proliferation Positive Regulation Of Apoptotic Process Involved In Morphogenesis Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Senescence-associated Heterochromatin Focus Ligase Inhibitor Activity Negative Regulation Of Immature T Cell Proliferation In Thymus Apoptotic Process Involved In Mammary Gland Involution Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Positive Regulation Of Anion Channel Activity Positive Regulation Of Enamel Mineralization Transepithelial Water Transport Chloride Channel Regulator Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Regulation Of Enamel Mineralization Positive Regulation Of Monoatomic Anion Transport Membrane Hyperpolarization Regulation Of Cardiolipin Metabolic Process Cardiolipin Acyl-chain Remodeling 1-acylglycerophosphocholine O-acyltransferase Activity Positive Regulation Of Cardiolipin Metabolic Process Negative Regulation Of Ubiquitin Protein Ligase Activity Positive Regulation Of Apoptotic Process Involved In Development Somatic Stem Cell Division Protein Localization To Nucleolus Negative Regulation Of Cyclin-dependent Protein Kinase Activity MDM2/MDM4 Family Protein Binding Regulation Of Membrane Potential Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Ubiquitin Ligase Inhibitor Activity Regulation Of Immature T Cell Proliferation In Thymus Regulation Of Protein Transport Negative Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Myeloid Cell Apoptotic Process Negative Regulation Of T Cell Differentiation In Thymus Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Localization Positive Regulation Of Protein Sumoylation Regulation Of Monoatomic Anion Transport Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Epithelial Fluid Transport
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