ESPN

Description		espin
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Microvillus Brush Border Filamentous Actin Stereocilium Stereocilium Tip Cell Projection Organelle Actin-based Cell Projection Cluster Of Actin-based Cell Projections
	Molecular Function	Actin Binding SH3 Domain Binding Actin Filament Binding
	Biological Process	Sensory Perception Of Sound Microvillar Actin Bundle Assembly Actin Filament Bundle Assembly
Pathways		Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases		Deafness, autosomal recessive
GWAS		Carotid intima media thickness x smoking interaction ( 32117412) Male-pattern baldness ( 29146897) Multiple sclerosis ( 31604244)
Interacting Genes		1 interacting genes: BAIAP2
Entrez ID		83715
HPRD ID		06962
Ensembl ID		ENSG00000187017
Uniprot IDs		B1AK53
PDB IDs
Enriched GO Terms of Interacting Partners?		Dendritic Spine Cytoplasm Neuron Projection Branch Point Neuron Projection Terminus Regulation Of Modification Of Postsynaptic Structure Response To L-glutamate Proline-rich Region Binding Cadherin Binding Involved In Cell-cell Adhesion Actin Crosslink Formation Postsynaptic Density, Intracellular Component Cellular Response To L-glutamate Regulation Of Modification Of Synaptic Structure Positive Regulation Of Dendritic Spine Morphogenesis Regulation Of Modification Of Postsynaptic Actin Cytoskeleton Cytoskeletal Anchor Activity Positive Regulation Of Dendrite Morphogenesis Positive Regulation Of Excitatory Postsynaptic Potential Positive Regulation Of Dendritic Spine Development Dendritic Shaft Transcription Coregulator Binding Presynaptic Cytosol Postsynaptic Cytosol Regulation Of Dendritic Spine Morphogenesis Excitatory Synapse Cellular Response To Epidermal Growth Factor Stimulus Dendrite Development Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Actin Filament Polymerization Response To Epidermal Growth Factor Regulation Of Dendritic Spine Development Regulation Of Dendrite Morphogenesis Protein Localization To Synapse Actin Filament Bundle Organization Synaptic Membrane Actin Filament Bundle Assembly Scaffold Protein Binding Positive Regulation Of Protein Polymerization Filopodium Protein Localization To Cell Junction Insulin Receptor Signaling Pathway Cellular Response To Amino Acid Stimulus PDZ Domain Binding Regulation Of Dendrite Development Schaffer Collateral - CA1 Synapse Secretory Granule Ruffle Response To Amino Acid Regulation Of Actin Filament Polymerization Plasma Membrane Organization Regulation Of Nervous System Process Regulation Of Actin Polymerization Or Depolymerization
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