KATNAL2

Name	katanin catalytic subunit A1 like 2
Structure	No pdb structure
Interactors	3 interactors: ACTN2 LNX1 UBC
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Spindle Cytoskeleton Microtubule Katanin Complex Microtubule Cytoskeleton
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Microtubule Binding Microtubule Severing ATPase Activity Isomerase Activity ATP Hydrolysis Activity
	Biological Process	Meiotic Spindle Organization Cytoplasmic Microtubule Organization Microtubule Severing
GWAS	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203 ) Conscientiousness ( 21173776 ) Femur bone mineral density x serum urate levels interaction ( 34046847 ) Fruit consumption ( 32066663 )
Entrez ID	83473
HPRD ID	13754
Ensembl ID	ENSG00000167216
Uniprot IDs	K7EIJ8 K7EPQ6 Q8IYT4
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Postsynaptic Cytoskeleton Organization Positive Regulation Of Endocytic Recycling Titin Z Domain Binding Structural Constituent Of Postsynaptic Actin Cytoskeleton Angiotensin-activated Signaling Pathway Negative Regulation Of Protein Localization To Cell Surface Positive Regulation Of Actin Filament Depolymerization Regulation Of Endocytic Recycling Postsynaptic Actin Cytoskeleton Titin Binding Postsynaptic Density, Intracellular Component Channel Activator Activity Postsynaptic Actin Cytoskeleton Organization Positive Regulation Of Protein Depolymerization Microspike Assembly Phospholipase C-activating Angiotensin-activated Signaling Pathway Actin Filament Uncapping FATZ Binding Cell Junction Organization Pseudopodium LIM Domain Binding Protein Ubiquitination Modification-dependent Protein Catabolic Process Protein Tag Activity Synapse Maturation Positive Regulation Of Cation Channel Activity Focal Adhesion Assembly Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Negative Regulation Of Potassium Ion Transport Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Potassium Ion Transport Regulation Of Protein Localization To Cell Surface Cell-substrate Junction Organization Positive Regulation Of Protein-containing Complex Disassembly Cell-substrate Junction Assembly Positive Regulation Of Transporter Activity Cardiac Muscle Cell Development Sarcomere Organization Post-translational Protein Modification Structural Constituent Of Muscle Cardiac Cell Development Hippocampal Mossy Fiber To CA3 Synapse Regulation Of Actin Filament Depolymerization Sarcomere Cortical Actin Cytoskeleton Macromolecule Catabolic Process Platelet Alpha Granule Lumen