HIST1H2AC

Gene Name		histone cluster 1, H2ac
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleosome Nucleus Extracellular Vesicular Exosome
	Molecular Function	Molecular_function DNA Binding Protein Heterodimerization Activity
	Biological Process	Biological_process
Pathways		RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Mitotic Prophase Regulatory RNA pathways RNA Polymerase I Promoter Clearance Deposition of new CENPA-containing nucleosomes at the centromere Cellular Senescence Signaling by Wnt HATs acetylate histones M Phase Amyloids NoRC negatively regulates rRNA expression Packaging Of Telomere Ends Telomere Maintenance Nucleosome assembly RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN DNA methylation Transcriptional regulation by small RNAs Meiotic recombination DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance HDACs deacetylate histones Chromatin organization misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling RNA Polymerase I Transcription formation of the beta-catenin:TCF transactivating complex Meiotic synapsis Epigenetic regulation of gene expression Senescence-Associated Secretory Phenotype (SASP) Negative epigenetic regulation of rRNA expression PRC2 methylates histones and DNA Cell Cycle, Mitotic RMTs methylate histone arginines Chromatin modifying enzymes Oxidative Stress Induced Senescence TCF dependent signaling in response to WNT RNA Polymerase I Promoter Opening SIRT1 negatively regulates rRNA Expression Signaling by WNT in cancer Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: TFAP2B
Entrez ID		8334
HPRD ID		09104
Ensembl ID		ENSG00000180573
Uniprot IDs		Q93077
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Creatinine Homeostasis Cellular Urea Homeostasis Cellular Ammonia Homeostasis Ammonia Homeostasis Urea Homeostasis Ductus Arteriosus Closure Distal Tubule Development Phosphate Ion Homeostasis Potassium Ion Homeostasis Collecting Duct Development Positive Regulation Of Urine Volume Magnesium Ion Homeostasis Sympathetic Nervous System Development Sodium Ion Homeostasis Aorta Morphogenesis Retina Layer Formation Aorta Development Renal Water Homeostasis Response To Lithium Ion Metanephric Nephron Development Autonomic Nervous System Development Anion Homeostasis Multicellular Organismal Water Homeostasis Neural Retina Development Forelimb Morphogenesis Artery Morphogenesis Retina Morphogenesis In Camera-type Eye Hindlimb Morphogenesis Positive Regulation Of Neuron Apoptotic Process Water Homeostasis Artery Development Positive Regulation Of Neuron Death Regulation Of BMP Signaling Pathway Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Renal System Process Renal Tubule Development Metanephros Development Fat Cell Differentiation Camera-type Eye Morphogenesis Glucose Metabolic Process Nephron Development Kidney Epithelium Development Eye Morphogenesis Retina Development In Camera-type Eye Negative Regulation Of Neuron Apoptotic Process Limb Morphogenesis Regulation Of Insulin Secretion Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Limb Development
Tagcloud ?		complement cytoplasm display examining fraction h2b hfob histone hmscs instead ionizing mesenchymal metazoan microarray mrnas osteoblast polyadenylated polyadenylation polyribosomes produce replication spliced transcripts transported tumorigenesis unlike varies