USP9Y

Description		ubiquitin specific peptidase 9 Y-linked
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol
	Molecular Function	Cysteine-type Deubiquitinase Activity Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity Metal Ion Binding Co-SMAD Binding
	Biological Process	Proteolysis Transforming Growth Factor Beta Receptor Signaling Pathway Spermatogenesis Cell Migration Protein Deubiquitination BMP Signaling Pathway Regulation Of Protein Stability
Pathways
Drugs
Diseases		Azoospermia, including: Azoospermia; Azoospermia due to perturbations of meiosis
GWAS
Novel Interacting Genes		1 novel interacting genes: PACS1
Interacting Genes		3 interacting genes: MAPT RSPH1 UBC
Entrez ID		8287
HPRD ID		02449
Ensembl ID		ENSG00000114374
Uniprot IDs		O00507
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone-dependent DNA Binding Tubulin Complex Microtubule Lateral Binding Main Axon Regulation Of Tubulin Deacetylation Negative Regulation Of Mitochondrial Fission Cellular Response To Brain-derived Neurotrophic Factor Stimulus Negative Regulation Of Tubulin Deacetylation Lipoprotein Particle Binding Neurofibrillary Tangle Assembly Inclusion Body Assembly Intracellular Distribution Of Mitochondria Minor Groove Of Adenine-thymine-rich DNA Binding Neurofibrillary Tangle Positive Regulation Of Protein Localization To Synapse Plus-end-directed Organelle Transport Along Microtubule Negative Regulation Of Establishment Of Protein Localization To Mitochondrion Outer Dense Fiber Radial Spoke Head 1 Radial Spoke Head 3 Radial Spoke Head Regulation Of Cellular Response To Heat Regulation Of Protein Deacetylation Regulation Of Long-term Synaptic Depression Phosphatidylinositol Bisphosphate Binding Negative Regulation Of Membrane Potential Axolemma Axonal Transport Of Mitochondrion Dynactin Binding Negative Regulation Of Mitochondrial Membrane Potential Protein Tag Activity COPI-coated Vesicle Meiotic Spindle Radial Spoke Somatodendritic Compartment Nuclear Periphery Microtubule Cytoskeleton Organization Apolipoprotein Binding Astrocyte Activation Mitochondrion Distribution Response To Lead Ion Positive Regulation Of Superoxide Anion Generation Generation Of Neurons Regulation Of Superoxide Anion Generation Microtubule Polymerization Protein Phosphatase 2A Binding Regulation Of Mitochondrial Fission Regulation Of Protein Localization To Synapse Amyloid Fibril Formation Regulation Of Superoxide Metabolic Process
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