CABLES2

Description		Cdk5 and Abl enzyme substrate 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol
	Molecular Function
	Biological Process	Cell Division Regulation Of Cell Cycle
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Colorectal cancer ( 29471430) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Prostate cancer ( 23535732)
Interacting Genes		4 interacting genes: ABL1 CDK3 CDK5 TP53
Entrez ID		81928
HPRD ID		12994
Ensembl ID		ENSG00000149679
Uniprot IDs		Q9BTV7
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Neuron Apoptotic Process Neuron Apoptotic Process Regulation Of Neuron Apoptotic Process Regulation Of Cell Cycle Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Cellular Senescence Negative Regulation Of Cell Cycle T Cell Differentiation In Thymus Regulation Of Autophagy Regulation Of Cell Growth Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Kinase Holoenzyme Complex Cerebellum Development Regulation Of Cell Cycle Phase Transition Cellular Senescence T Cell Proliferation Positive Regulation Of Apoptotic Process Negative Regulation Of Protein Ubiquitination Positive Regulation Of Programmed Cell Death Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Axon Extension Regulation Of Mitotic Cell Cycle Protein Kinase Activity P53 Binding Regulation Of Growth Associative Learning Regulation Of Fibroblast Proliferation Negative Regulation Of Protein Metabolic Process Negative Regulation Of Post-translational Protein Modification Hematopoietic Or Lymphoid Organ Development Kinase Activity Protein Localization To Cytoplasmic Microtubule Plus-end Negative Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Presynaptic Cytosolic Calcium Concentration Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Glial Cell Differentiation Lymphocyte Activation Involved In Immune Response Mononuclear Cell Proliferation Cell Population Proliferation Lymphocyte Proliferation Regulation Of Cell Cycle Process Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Cytosolic Calcium Ion Concentration Transitional One Stage B Cell Differentiation Regulation Of Cell Development T Cell Differentiation Cellular Response To Oxygen-containing Compound DNA Damage Response Cell Activation Involved In Immune Response
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