NPRL3

Description		NPR3 like, GATOR1 complex subunit
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GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Membrane GATOR1 Complex
	Molecular Function	GTPase Activator Activity Protein Binding
	Biological Process	Ventricular Septum Development Positive Regulation Of Autophagy Negative Regulation Of TOR Signaling Cellular Response To Amino Acid Starvation Aorta Morphogenesis Cardiac Muscle Tissue Development Roof Of Mouth Development Negative Regulation Of TORC1 Signaling
Pathways		Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Cardiometabolic and hematological traits ( 27668658) Hemoglobin ( 32888494) Hemoglobin levels ( 26366553 32327693) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Mean corpuscular hemoglobin ( 27863252 32888494 28453575 29403010) Mean corpuscular hemoglobin concentration ( 32888494 27863252 29403010) Mean corpuscular volume ( 28453575 32888494 29403010 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 29403010 27863252 32888494) Red blood cell traits ( 23222517 23446634) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 27863252 32888494) Serum metabolite levels ( 33031748) Sickle cell anemia (haemolysis) ( 23406172)
Interacting Genes		4 interacting genes: APPBP2 FHL3 SESN3 UBC
Entrez ID		8131
HPRD ID		11866
Ensembl ID		ENSG00000103148
Uniprot IDs		B7Z220 B7Z6Q0 Q12980 Q9BTE2
PDB IDs		6CES 6CET 7T3A 7T3B 7T3C 8FW5
Enriched GO Terms of Interacting Partners?
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