ST8SIA2

Description		ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Nucleoplasm Early Endosome Golgi Apparatus Cytosol Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	Nucleotide Binding Alpha-N-acetylneuraminate Alpha-2,8-sialyltransferase Activity Sialyltransferase Activity Transferase Activity Glycosyltransferase Activity Sialic Acid Binding
	Biological Process	Ganglioside Biosynthetic Process Carbohydrate Metabolic Process Protein Glycosylation N-glycan Processing Nervous System Development Oligosaccharide Metabolic Process Neuron Differentiation Protein Modification Process Response To Cocaine Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Synapse Assembly Sialylation Neuron Projection Extension
Pathways		Sialic acid metabolism NCAM1 interactions N-Glycan antennae elongation
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378) Allergic rhinitis ( 25085501) Bipolar I disorder ( 20386566) Colorectal cancer (diet interaction) ( 24743840) Femur bone mineral density x serum urate levels interaction ( 34046847) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Smoking initiation ( 24665060) Weight loss (gastric bypass surgery) ( 23643386)
Interacting Genes		1 interacting genes: NCAM1
Entrez ID		8128
HPRD ID		03969
Ensembl ID		ENSG00000140557
Uniprot IDs		B2R9U8 C6G488 Q4VAY9 Q92186
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Semaphorin-plexin Signaling Pathway Commissural Neuron Axon Guidance Epithelial To Mesenchymal Transition Mesenchymal Cell Differentiation Symbiont Entry Into Host Cell Side Of Membrane Virus Receptor Activity Biological Process Involved In Interaction With Host Axon Guidance Neuron Projection Guidance
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