AAAS

Description		aladin WD repeat nucleoporin
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GO Annotations	Cellular Component	Spindle Pole Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Cytoplasm Centrosome Cytosol Cytoskeleton Membrane Nuclear Membrane Mitotic Spindle
	Molecular Function	Protein Binding
	Biological Process	Microtubule Bundle Formation Glutathione Metabolic Process Nucleocytoplasmic Transport Response To Oxidative Stress Learning Fertilization Protein Transport Multicellular Organism Growth Regulation Of Nucleocytoplasmic Transport MRNA Transport Mitotic Spindle Assembly
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus RHOA GTPase cycle HCMV Early Events HCMV Late Events SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS
Interacting Genes		2 interacting genes: FILNC1 REL
Entrez ID		8086
HPRD ID		05646
Ensembl ID		ENSG00000094914
Uniprot IDs		Q9NRG9
PDB IDs		7R5J 7R5K
Enriched GO Terms of Interacting Partners?		NF-kappaB Complex
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