DDHD1

Description		DDHD domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Phospholipase Activity Protein Binding Phospholipase A1 Activity Hydrolase Activity Metal Ion Binding
	Biological Process	Lipid Metabolic Process Phosphatidylinositol Metabolic Process Positive Regulation Of Mitochondrial Fission
Pathways		Synthesis of PA
Drugs
Diseases
GWAS		Chin dimples ( 27182965) Lung function (FEV1/FVC) ( 30061609) Optic cup area ( 25631615 28073927 31798171) Platelet count ( 32888494) Platelet distribution width ( 32888494) Prostate cancer ( 23535732) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
Interacting Genes		2 interacting genes: CR1L ZBTB24
Entrez ID		80821
HPRD ID		07482
Ensembl ID		ENSG00000100523
Uniprot IDs		Q8NEL9
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of Complement-dependent Cytotoxicity Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Negative Regulation Of Complement Activation, Classical Pathway Negative Regulation Of Complement Activation Regulation Of Complement Activation T Cell Mediated Immunity Regulation Of Humoral Immune Response Negative Regulation Of Adaptive Immune Response Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Hematopoietic Progenitor Cell Differentiation Lymphocyte Mediated Immunity
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