SSPN

Description		sarcospan
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Plasma Membrane Dystrophin-associated Glycoprotein Complex Membrane Transport Vesicle Sarcolemma Synapse Postsynaptic Membrane
	Molecular Function
	Biological Process	Muscle Contraction Cell Adhesion
Pathways		Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
Drugs
Diseases
GWAS		A body shape index ( 34021172) Alanine aminotransferase levels ( 33547301) Atrial fibrillation ( 30061737 29892015) Endometrial cancer ( 30093612) Endometrial cancer (endometrioid histology) ( 30093612) HDL cholesterol levels ( 32203549) HDL cholesterol levels in HIV infection ( 33109212) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Hypertrophic cardiomyopathy (sarcomere negative) ( 33495597) Lymphocyte count ( 32888494) Male-pattern baldness ( 28196072 29146897 27182965) PR interval ( 32439900) Serum alkaline phosphatase levels ( 33547301) Triglyceride levels ( 32203549) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 28448500 34021172) Waist-hip index ( 34021172) Waist-hip ratio ( 25673412 20935629) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 28448500 25673412) White blood cell count ( 32888494)
Interacting Genes		2 interacting genes: SGCG SMO
Entrez ID		8082
HPRD ID		03359
Ensembl ID		ENSG00000123096
Uniprot IDs		Q14714
PDB IDs
Enriched GO Terms of Interacting Partners?		Muscle Tissue Development Mesenchymal To Epithelial Transition Involved In Metanephric Renal Vesicle Formation Ventral Midline Determination Gene Expression Dystroglycan Complex Contact Inhibition Cerebellar Cortex Morphogenesis Detection Of Cell Density Epithelial-mesenchymal Cell Signaling Pancreas Morphogenesis Response To Inositol Negative Regulation Of Hair Follicle Development Sarcoglycan Complex Tissue Development Determination Of Left/right Asymmetry In Lateral Mesoderm Commissural Neuron Axon Guidance Thalamus Development Cellular Response To Cholesterol Spinal Cord Dorsal/ventral Patterning Somite Development CAMP-dependent Protein Kinase Inhibitor Activity Midgut Development Regulation Of Somatic Stem Cell Population Maintenance Mesenchymal To Epithelial Transition Myoblast Migration Left/right Axis Specification Atrial Septum Morphogenesis Dorsal/ventral Neural Tube Patterning Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Patched Binding 9+0 Non-motile Cilium Oxysterol Binding Protein Kinase A Catalytic Subunit Binding Forebrain Morphogenesis Regulation Of Heart Morphogenesis Type B Pancreatic Cell Development Mammary Gland Epithelial Cell Differentiation Negative Regulation Of DNA Binding Astrocyte Activation Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Cellular Response To Sterol Regulation Of Hair Follicle Development Smooth Muscle Tissue Development Regulation Of Branching Involved In Ureteric Bud Morphogenesis Heart Contraction Regulation Of Hair Cycle Dentate Gyrus Development Response To Cholesterol Plasma Membrane Bounded Cell Projection Skeletal Muscle Fiber Development
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