ARHGAP39

Description		Rho GTPase activating protein 39
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytoskeleton Glutamatergic Synapse
	Molecular Function	GTPase Activator Activity
	Biological Process	Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Postsynapse Organization
Pathways		Inactivation of CDC42 and RAC1 RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle
Drugs
Diseases
GWAS		Educational attainment ( 25201988)
Interacting Genes		2 interacting genes: CDC42 RAC1
Entrez ID		80728
HPRD ID		17224
Ensembl ID		ENSG00000147799
Uniprot IDs		B3KS00 B4DK23 Q9C0H5
PDB IDs
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Thioesterase Binding GTP-dependent Protein Binding Positive Regulation Of Lamellipodium Organization Positive Regulation Of Lamellipodium Assembly Wnt Signaling Pathway, Planar Cell Polarity Pathway Phagocytosis, Engulfment Regulation Of Lamellipodium Assembly Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Membrane Invagination Positive Regulation Of Stress Fiber Assembly Regulation Of Lamellipodium Organization Non-canonical Wnt Signaling Pathway Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Actin Filament Bundle Assembly G Protein Activity Cytoplasmic Ribonucleoprotein Granule Regulation Of Stress Fiber Assembly Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Positive Regulation Of Cell-substrate Adhesion Regulation Of Postsynapse Organization Establishment Or Maintenance Of Cell Polarity Positive Regulation Of Supramolecular Fiber Organization Cell-cell Junction Organization Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Cell Projection Assembly Regulation Of Actin Filament Organization Actin Filament Organization Small GTPase-mediated Signal Transduction Neuron Projection Morphogenesis Postsynapse GBD Domain Binding Storage Vacuole Regulation Of Cell-substrate Adhesion Positive Regulation Of Ovarian Follicle Development Negative Regulation Of Interleukin-23 Production Regulation Of ERK5 Cascade Angiotensin-activated Signaling Pathway Involved In Heart Process Embryonic Olfactory Bulb Interneuron Precursor Migration Cerebral Cortex GABAergic Interneuron Development Wnt Signaling Pathway Cell Projection Morphogenesis Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Synapse Organization GTPase Activity Endothelin Receptor Signaling Pathway Involved In Heart Process Regulation Of Endocytosis Rho GDP-dissociation Inhibitor Binding Regulation Of Cell Adhesion Involved In Heart Morphogenesis
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