ELL3

Description		elongation factor for RNA polymerase II 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nucleolus Cytosol Transcription Elongation Factor Complex Nuclear Speck Cell Junction
	Molecular Function	Cis-regulatory Region Sequence-specific DNA Binding Protein Binding
	Biological Process	DNA-templated Transcription Elongation Transcription By RNA Polymerase II Transcription Elongation By RNA Polymerase II Spermatogenesis Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription Elongation By RNA Polymerase II Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator SnRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Stem Cell Differentiation Positive Regulation Of Neurogenesis Neural Precursor Cell Proliferation Stem Cell Proliferation Signal Transduction By P53 Class Mediator Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Neural Precursor Cell Proliferation Positive Regulation Of Stem Cell Proliferation
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS
Interacting Genes		2 interacting genes: FTH1 TP53
Entrez ID		80237
HPRD ID		10933
Ensembl ID		ENSG00000128886
Uniprot IDs		Q9HB65
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Fibroblast Proliferation Regulation Of Fibroblast Proliferation Ferritin Complex Ferroxidase Activity Iron Ion Sequestering Activity Oligodendrocyte Apoptotic Process Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Negative Regulation Of Pentose-phosphate Shunt Negative Regulation Of Helicase Activity Oxidative Stress-induced Premature Senescence Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Negative Regulation Of G1 To G0 Transition Glucose Catabolic Process To Lactate Via Pyruvate Germ Cell Nucleus Cellular Response To Actinomycin D Histone Deacetylase Regulator Activity Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Response To Actinomycin D T Cell Proliferation Involved In Immune Response Regulation Of G1 To G0 Transition Glial Cell Apoptotic Process Cellular Response To UV-C ATP-dependent DNA/DNA Annealing Activity B Cell Lineage Commitment Regulation Of Pentose-phosphate Shunt Ferric Iron Binding Mitochondrial DNA Repair Bone Marrow Development Stress-induced Premature Senescence Regulation Of NADP Metabolic Process Negative Regulation Of MiRNA Processing Negative Regulation Of Cell Population Proliferation Regulation Of Ferroptosis Autolysosome Negative Regulation Of Ferroptosis Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Cellular Senescence Negative Regulation Of MiRNA-mediated Gene Silencing Regulation Of MiRNA Processing Regulation Of Thymocyte Apoptotic Process Thymocyte Apoptotic Process Negative Regulation Of ATP-dependent Activity ER Overload Response Mitotic G1 DNA Damage Checkpoint Signaling MDM2/MDM4 Family Protein Binding TFIID-class Transcription Factor Complex Binding Replicative Senescence Positive Regulation Of Programmed Necrotic Cell Death
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