CPED1

Description		cadherin like and PC-esterase domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum
	Molecular Function
	Biological Process
Pathways
Drugs
Diseases
GWAS		Bone mineral density (paediatric, lower limb) ( 24945404) Bone mineral density (paediatric, skull) ( 24945404) Bone mineral density (paediatric, total body less head) ( 24945404 28743860) Bone mineral density (paediatric, upper limb) ( 24945404) Brain morphology (MOSTest) ( 32665545) Fractures ( 30158200) Heel bone mineral density ( 28869591 30598549) Mean reticulocyte volume ( 32888494) Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Pediatric areal bone mineral density (radius vs spine & hip discordant skeletal phenotype) ( 29240982) Pediatric areal bone mineral density (radius) ( 28181694 26041818) Pediatric bone mineral content (femoral neck) ( 28181694) Pediatric bone mineral content (radius) ( 28181694 26041818) Subcortical volume (MOSTest) ( 32665545) TB-LM or TBLH-BMD (pleiotropy) ( 28743860) Type 2 diabetes ( 30130595) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172)
Interacting Genes		1 interacting genes: APP
Entrez ID		79974
HPRD ID		08647
Ensembl ID		ENSG00000106034
Uniprot IDs		A4D0V7 Q9H6Q5
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Neuron Projection Maintenance RAGE Receptor Binding
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