ATAT1

Description		alpha tubulin acetyltransferase 1
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GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Spindle Cytosol Cytoskeleton Microtubule Clathrin-coated Pit Focal Adhesion Membrane Axon Cell Projection Anchoring Junction Mitotic Spindle Microtubule Bundle
	Molecular Function	L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Protein Binding Acetyltransferase Activity Transferase Activity Acyltransferase Activity Tubulin N-acetyltransferase Activity
	Biological Process	Microtubule Cytoskeleton Organization Spermatogenesis Response To Mechanical Stimulus Dentate Gyrus Development NLRP3 Inflammasome Complex Assembly Regulation Of Fat Cell Differentiation Response To Pain Neuron Development Cilium Assembly Regulation Of Microtubule Cytoskeleton Organization Alpha-tubulin Acetylation Positive Regulation Of NLRP3 Inflammasome Complex Assembly
Pathways		Cargo trafficking to the periciliary membrane
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Prostate cancer ( 29892016)
Interacting Genes		3 interacting genes: APP FBXO7 SRPK2
Entrez ID		79969
HPRD ID		12850
Ensembl ID		ENSG00000137343
Uniprot IDs		A0A1U9X797 B7Z4Q7 Q5SQI0
PDB IDs		3VWD 3VWE 4B5O 4B5P 4GS4 4IF5 4PK2 4PK3 4U9Y 4U9Z
Enriched GO Terms of Interacting Partners?		Regulation Of Neuron Apoptotic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Positive Regulation Of Neuron Apoptotic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Acetylcholine Receptor Activator Activity PTB Domain Binding Presynapse Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Apoptotic Process Lipoprotein Particle Regulation Of Programmed Cell Death Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Cell Cycle Nuclear Speck Organization Lewy Body Core Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Positive Regulation Of Cell Cycle Protein Heterodimerization Activity Axon Choice Point Recognition Immune System Process Heparan Sulfate Binding Signaling Receptor Activator Activity
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