LPCAT1

Description		lysophosphatidylcholine acyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Plasma Membrane Membrane Azurophil Granule Membrane
	Molecular Function	1-acylglycerol-3-phosphate O-acyltransferase Activity Calcium Ion Binding O-acyltransferase Activity Transferase Activity Acyltransferase Activity Lysophosphatidic Acid Acyltransferase Activity Metal Ion Binding 2-acylglycerol-3-phosphate O-acyltransferase Activity Plasmalogen Synthase Activity 1-acylglycerophosphocholine O-acyltransferase Activity 1-alkylglycerophosphocholine O-acyltransferase Activity 1-alkylglycerophosphocholine O-acetyltransferase Activity
	Biological Process	Lipid Metabolic Process Phospholipid Metabolic Process Phosphatidic Acid Biosynthetic Process Phosphatidylcholine Biosynthetic Process Phospholipid Biosynthetic Process Protein Catabolic Process Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylcholine Acyl-chain Remodeling Surfactant Homeostasis Positive Regulation Of Protein Catabolic Process Retina Development In Camera-type Eye Negative Regulation Of Phosphatidylcholine Biosynthetic Process
Pathways		Acyl chain remodelling of PC Acyl chain remodelling of PG Synthesis of PA Synthesis of PC Neutrophil degranulation
Drugs
Diseases
GWAS		Lung adenocarcinoma ( 28604730) Lung cancer in ever smokers ( 28604730) Multiple sclerosis ( 31604244) Pancreatic cancer ( 25086665)
Interacting Genes		3 interacting genes: BTRC GSK3B OGT
Entrez ID		79888
HPRD ID		08572
Ensembl ID		ENSG00000153395
Uniprot IDs		Q8NF37
PDB IDs
Enriched GO Terms of Interacting Partners?		TOR Signaling Regulation Of TOR Signaling Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Rhythmic Process Regulation Of Proteolysis Regulation Of Protein Catabolic Process Negative Regulation Of Catabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process TORC1 Signaling Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Organelle Assembly Negative Regulation Of TOR Signaling Beta-catenin Binding Positive Regulation Of Protein Metabolic Process Regulation Of TORC1 Signaling Regulation Of Circadian Rhythm Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of Protein Catabolic Process Regulation Of Microtubule Anchoring At Centrosome Circadian Rhythm Regulation Of Generation Of Precursor Metabolites And Energy Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Proteolysis Positive Regulation Of Translation Superior Temporal Gyrus Development Negative Regulation Of Type B Pancreatic Cell Development Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Autophagy Negative Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Glycogen (starch) Synthase Activity Proteolysis Protein Phosphorylated Amino Acid Binding Regulation Of Protein Ubiquitination Protein O-acetylglucosaminyltransferase Activity Negative Regulation Of Signal Transduction Regulation Of Canonical Wnt Signaling Pathway Regulation Of Protein Metabolic Process Negative Regulation Of Signaling Negative Regulation Of TORC2 Signaling Negative Regulation Of Dopaminergic Neuron Differentiation Regulation Of Glycogen (starch) Synthase Activity Negative Regulation Of Cell Communication Regulation Of Post-translational Protein Modification Cellular Response To Nutrient Levels
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