TCTN2

Description		tectonic family member 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Membrane Ciliary Transition Zone MKS Complex Cell Projection Ciliary Membrane
	Molecular Function
	Biological Process	Smoothened Signaling Pathway Cell Projection Organization Cilium Assembly Protein Localization To Ciliary Transition Zone
Pathways		Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Novel Interacting Genes		3 novel interacting genes: CCDC92 COQ5 KDM2B
Interacting Genes
Entrez ID		79867
HPRD ID		07805
Ensembl ID		ENSG00000168778
Uniprot IDs		A0A7P0T8X4 Q96GX1
PDB IDs
Enriched GO Terms of Interacting Partners?		2-methoxy-6-polyprenyl-1,4-benzoquinol Methyltransferase Activity Initiation Of Neural Tube Closure Fourth Ventricle Development Midbrain-hindbrain Boundary Morphogenesis Histone H3K36me/H3K36me2 Demethylase Activity Third Ventricle Development Extrinsic Component Of Mitochondrial Inner Membrane Ubiquinone Biosynthesis Complex Histone H3K36 Demethylase Activity Unmethylated CpG Binding Ubiquinone Biosynthetic Process Embryonic Camera-type Eye Morphogenesis Lateral Ventricle Development Ubiquinone Metabolic Process Quinone Metabolic Process Histone Demethylase Activity Hindbrain Development Negative Regulation Of Neural Precursor Cell Proliferation PcG Protein Complex Embryonic Eye Morphogenesis Ketone Biosynthetic Process Midbrain Development RRNA Binding
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