TTLL7

Description		tubulin tyrosine ligase like 7
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Microtubule Cilium Dendrite Ciliary Basal Body Cell Projection Perikaryon
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Tubulin Binding Ligase Activity Alpha-tubulin Binding Metal Ion Binding Beta-tubulin Binding Tubulin-glutamic Acid Ligase Activity Protein-glutamic Acid Ligase Activity, Initiating Protein-glutamic Acid Ligase Activity, Elongating
	Biological Process	Microtubule Cytoskeleton Organization Nervous System Development Protein Polyglutamylation Cell Differentiation
Pathways		Carboxyterminal post-translational modifications of tubulin
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Alzheimer's disease ( 20061627) Body mass index ( 25673413) General risk tolerance (MTAG) ( 30643258) Mental health study participation (completed survey) ( 31263887) Mild influenza (H1N1) infection ( 26379185) Obesity-related traits ( 23251661) Response to taxane treatment (docetaxel) ( 23006423) Tenofovir clearance in HIV infection ( 26148204) Time-dependent creatinine clearance change response to tenofovir treatment in HIV infection (time and treatment arm interaction) ( 26148204) Toenail selenium levels ( 25343990)
Interacting Genes		3 interacting genes: APP LMO4 ZDHHC17
Entrez ID		79739
HPRD ID		08013
Ensembl ID		ENSG00000137941
Uniprot IDs		Q6ZT98
PDB IDs		4YLR 4YLS
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Cell Projection Morphogenesis Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Regulation Of ERK1 And ERK2 Cascade Axon Midline Choice Point Recognition Amylin Binding Neuron Projection Morphogenesis Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Cell Projection Organization Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Axonogenesis Low-density Lipoprotein Particle Mediated Signaling Ventral Spinal Cord Interneuron Differentiation Protein-cysteine S-myristoyltransferase Activity Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Perforant Pathway To Dendrate Granule Cell Synapse Regulation Of Spontaneous Synaptic Transmission Positive Regulation Of Phosphate Metabolic Process Regulation Of Synapse Organization NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Protein-cysteine S-stearoyltransferase Activity Axon Choice Point Recognition Spinal Cord Motor Neuron Cell Fate Specification Heparan Sulfate Binding Signaling Receptor Activator Activity Signaling Receptor Binding Peptidase Activator Activity
Tagcloud ?