IPO4

Description		importin 4
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GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm Membrane Protein-containing Complex
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Small GTPase Binding Nuclear Import Signal Receptor Activity
	Biological Process	Protein Import Into Nucleus Intracellular Protein Transport Protein Transport Protein Localization To Nucleus
Pathways
Drugs
Diseases
GWAS
Interacting Genes		9 interacting genes: APP HGS LINC01554 MTNR1B NXF1 RAN RNF10 TCP11L1 VAV2
Entrez ID		79711
HPRD ID		07022
Ensembl ID		ENSG00000196497
Uniprot IDs		B3KT38 Q8TEX9
PDB IDs		5XAH 5XBK 7UNK 8DYO
Enriched GO Terms of Interacting Partners?		Regulation Of Nervous System Process Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Regulation Of Spontaneous Synaptic Transmission Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Intracellular Transport Regulation Of Response To Calcium Ion Regulation Of Establishment Of Protein Localization Axon Midline Choice Point Recognition Recycling Endosome NMDA Selective Glutamate Receptor Signaling Pathway Amylin Binding Regulation Of Synapse Structure Or Activity Endosome To Plasma Membrane Transport Vesicle Negative Regulation Of Multicellular Organismal Process Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Toll Signaling Pathway Regulation Of System Process Lipoprotein Particle Regulation Of Protein Transport Regulation Of Protein Localization To Nucleus Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Melatonin Receptor Activity Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of CGMP-mediated Signaling Regulation Of Neuronal Action Potential Negative Regulation Of Transmission Of Nerve Impulse Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep RNA Export From Nucleus RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Nuclear Export
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