PRKRIP1

Description		PRKR interacting protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Extracellular Exosome
	Molecular Function	Double-stranded RNA Binding Protein Kinase Inhibitor Activity Protein Binding Protein Kinase Binding
	Biological Process	Renal System Process MRNA Processing RNA Splicing
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: APP CEBPA CEP70 EIF2AK2 GSK3B MAGEA11 TRAF2
Entrez ID		79706
HPRD ID		11460
Ensembl ID		ENSG00000128563
Uniprot IDs		Q9H875
PDB IDs		5XJC 6ICZ 6QDV 7W5A 7W5B 8C6J 9FMD
Enriched GO Terms of Interacting Partners?		Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Gene Expression Response To Peptide Response To Cytokine Regulation Of Hematopoietic Stem Cell Proliferation TORC2 Signaling Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Macromolecule Metabolic Process Response To Endoplasmic Reticulum Stress Regulation Of Protein Metabolic Process Negative Regulation Of Metabolic Process Neuron Projection Organization Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Protein Localization To Nucleus Intracellular Signal Transduction Positive Regulation Of Protein Metabolic Process Regulation Of DNA-templated Transcription Intracellular Signaling Cassette Regulation Of RNA Biosynthetic Process Cellular Response To Amyloid-beta Identical Protein Binding Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of RNA Metabolic Process Regulation Of Translation Positive Regulation Of Chemokine Production Regulation Of Response To Calcium Ion Positive Regulation Of Neuron Apoptotic Process Amylin Binding Response To Amyloid-beta Regulation Of Proteolysis Positive Regulation Of Toll Signaling Pathway Regulation Of Protein Catabolic Process Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of Apoptotic Signaling Pathway RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Stem Cell Differentiation Regulation Of Microtubule Anchoring At Centrosome Translational Initiation Positive Regulation Of NF-kappaB Transcription Factor Activity TORC2 Complex Disassembly Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process TOR Signaling Regulation Of Protein-containing Complex Assembly Regulation Of Stem Cell Proliferation Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Intracellular Signal Transduction
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