MANEA

Description		mannosidase endo-alpha
Image
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Alpha-mannosidase Activity Glycoprotein Endo-alpha-1,2-mannosidase Activity Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds
	Biological Process
Pathways		N-glycan trimming and elongation in the cis-Golgi
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Blood protein levels ( 30072576) Parkinson's disease ( 26227905)
Interacting Genes		1 interacting genes: DNM2
Entrez ID		79694
HPRD ID		14357
Ensembl ID		ENSG00000172469
Uniprot IDs		Q5SRI9
PDB IDs		6ZDC 6ZDF 6ZDK 6ZDL 6ZFA 6ZFN 6ZFQ 6ZJ1 6ZJ5
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Membrane Tubulation Vesicle Scission Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Membrane Tubulation Transferrin Transport Uropod Regulation Of Plasma Membrane Organization Antigen Processing And Presentation Of Exogenous Antigen Membrane Fission Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Iron Ion Transport Centrosome Cycle Synaptic Vesicle Transport Contractile Actin Filament Bundle Assembly Vesicle Budding From Membrane Stress Fiber Assembly Phagocytic Cup Antigen Processing And Presentation Of Exogenous Peptide Antigen Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Podosome G2/M Transition Of Mitotic Cell Cycle Antigen Processing And Presentation Of Peptide Antigen Endocytic Vesicle Membrane Receptor Internalization Cell Cycle G2/M Phase Transition Clathrin-coated Vesicle Actin Filament Bundle Organization Clathrin-coated Pit Regulation Of Axon Extension Protein Polymerization Actin Filament Bundle Assembly Phagocytic Vesicle Membrane Phosphatidylinositol-4,5-bisphosphate Binding Microtubule Organizing Center Organization Phagocytosis Antigen Processing And Presentation Post-Golgi Vesicle-mediated Transport Establishment Of Vesicle Localization SH3 Domain Binding Actomyosin Structure Organization Vesicle Localization Growth Cone Recycling Endosome Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Centriole Receptor-mediated Endocytosis Midbody Presynapse
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