TUT7

Description		terminal uridylyl transferase 7
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Transferase Activity Nucleotidyltransferase Activity MiRNA Binding Metal Ion Binding RNA Uridylyltransferase Activity Uridylyltransferase Activity
	Biological Process	Oocyte Maturation MiRNA Metabolic Process Pre-miRNA Processing RNA 3'-end Processing Histone MRNA Catabolic Process Transposable Element Silencing By MRNA Destabilization Polyuridylation-dependent MRNA Catabolic Process
Pathways		Deadenylation of mRNA Zygotic genome activation (ZGA) Z-decay: degradation of maternal mRNAs by zygotically expressed factors
Drugs
Diseases
GWAS
Interacting Genes		15 interacting genes: APP MIR138-2 MIR25 MIRLET7A1 MIRLET7A2 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I RNF10 ZDHHC17
Entrez ID		79670
HPRD ID		11697
Ensembl ID		ENSG00000083223
Uniprot IDs		Q5VYS8 Q96KX5 X6R3Q3
PDB IDs		5W0B 5W0M 5W0N 5W0O 8OEF 8OPP 8OPS 8OPT
Enriched GO Terms of Interacting Partners?		RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression MRNA Base-pairing Post-transcriptional Repressor Activity Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Extracellular Vesicle Negative Regulation Of Interleukin-6-mediated Signaling Pathway MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Space Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process MRNA Destabilization RNA Destabilization Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of MRNA Catabolic Process Regulation Of Metabolic Process Positive Regulation Of MRNA Metabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of MRNA Stability Regulation Of RNA Stability Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Negative Regulation Of Cytokine-mediated Signaling Pathway Negative Regulation Of Response To Cytokine Stimulus Positive Regulation Of Catabolic Process Negative Regulation Of Signal Transduction Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of MRNA Metabolic Process Negative Regulation Of Receptor Signaling Pathway Via STAT Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Regulation Of Cytokine-mediated Signaling Pathway Regulation Of Endothelial Cell Migration Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Perforant Pathway To Dendrate Granule Cell Synapse
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