NEIL1

Gene Name		nei endonuclease VIII-like 1 (E. coli)
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytoplasm Microtubule Organizing Center
	Molecular Function	Damaged DNA Binding DNA-(apurinic Or Apyrimidinic Site) Lyase Activity Protein C-terminus Binding Zinc Ion Binding Hydrolase Activity, Acting On Glycosyl Bonds DNA N-glycosylase Activity
	Biological Process	DNA Catabolic Process, Endonucleolytic Base-excision Repair Nucleotide-excision Repair Response To Oxidative Stress Negative Regulation Of Nuclease Activity
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: APP LIG3 POLB XRCC1
Entrez ID		79661
HPRD ID		12314
Ensembl ID		ENSG00000140398
Uniprot IDs		Q96FI4
PDB IDs		1TDH
Enriched GO Terms of Interacting Partners?		Base-excision Repair Neuron Apoptotic Process Neuron Death DNA Repair DNA-dependent DNA Replication DNA Biosynthetic Process Cellular Response To DNA Damage Stimulus Synaptic Growth At Neuromuscular Junction DNA Metabolic Process Response To Stress Collateral Sprouting In Absence Of Injury Base-excision Repair, DNA Ligation Otolith Morphogenesis Collateral Sprouting Axon Midline Choice Point Recognition Base-excision Repair, Gap-filling DNA Replication Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Lagging Strand Elongation Cellular Response To Stress Otolith Development Axon Choice Point Recognition Mitochondrial DNA Repair DNA Ligation Involved In DNA Repair Nucleobase-containing Compound Metabolic Process Neuron Remodeling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Pyrimidine Dimer Repair DNA Ligation Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Single Strand Break Repair Cellular Copper Ion Homeostasis Mitochondrial DNA Metabolic Process Double-strand Break Repair Via Nonhomologous End Joining Negative Regulation Of DNA Recombination Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle DNA Strand Elongation Involved In DNA Replication Mitochondrial Genome Maintenance Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity DNA Strand Elongation Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Cellular Response To Stimulus RNA Polyadenylation
Tagcloud ?		absent allowing apex1 arrest arresting brdu bromodeoxyuridine delay excision exerts glycosylase hepatectomy hours incompletely ko ogg1 oxidized oxodgtpase pcna ph proliferating reaching repair restoration seventy udg vital wt