FAT4

Description		FAT atypical cadherin 4
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GO Annotations	Cellular Component	Plasma Membrane Adherens Junction Membrane Extracellular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding
	Biological Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Axonogenesis Anatomical Structure Morphogenesis Cerebral Cortex Development Neurogenesis Epithelial Cell Differentiation Hippo Signaling Cell-cell Adhesion Mediated By Cadherin Generation Of Neurons Epithelium Development Cell-cell Adhesion
Pathways
Drugs
Diseases
GWAS		Bipolar disorder or major depressive disorder ( 20351715) Bone mineral density (spine) ( 26911590) Cerebrospinal fluid AB1-42 levels ( 26252872) Chin dimples ( 27182965) Cognitive performance ( 19734545) Memory dysfunction in frontotemporal lobe dementia ( 29724592) Pelvic organ prolapse ( 32184442) Small vessel stroke ( 29123153) Triglyceride levels in HIV infection ( 33109212) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		1 interacting genes: ATXN1
Entrez ID		79633
HPRD ID		07637
Ensembl ID		ENSG00000196159
Uniprot IDs		A0A6Q8JR05 A0A7P0T1I0 B3KU84 Q6V0I7 X2G5I7 X2GA70
PDB IDs		8EGW 8EGX
Enriched GO Terms of Interacting Partners?		Poly(G) Binding POZ Domain Binding Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Nuclear Inclusion Body Poly(U) RNA Binding Positive Regulation Of Glial Cell Proliferation Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Visual Behavior Visual Learning Regulation Of Glial Cell Proliferation Positive Regulation Of Gliogenesis Excitatory Postsynaptic Potential Social Behavior Insulin-like Growth Factor Receptor Signaling Pathway Lung Alveolus Development Adult Locomotory Behavior Regulation Of Gliogenesis Associative Learning Regulation Of Postsynaptic Membrane Potential Nuclear Export Nuclear Matrix Memory
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