NOX5

Description		NADPH oxidase 5
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane NADPH Oxidase Complex
	Molecular Function	Calcium Ion Binding Protein Binding Proton Channel Activity Superoxide-generating NAD(P)H Oxidase Activity Oxidoreductase Activity Heme Binding Metal Ion Binding Flavin Adenine Dinucleotide Binding NADP Binding Oxidoreductase Activity, Acting On NAD(P)H, Oxygen As Acceptor Superoxide-generating NADPH Oxidase Activity
	Biological Process	Angiogenesis Positive Regulation Of Cytokine Production Endothelial Cell Proliferation Monoatomic Ion Transport Apoptotic Process Defense Response Monoatomic Ion Transmembrane Transport Superoxide Anion Generation Regulation Of Fusion Of Sperm To Egg Plasma Membrane Cytoskeleton-dependent Cytokinesis Proton Transmembrane Transport Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS		Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Lipoprotein-associated phospholipase A2 activity change in response to statin therapy ( 23118302) Mean arterial pressure ( 27618448) Obesity-related traits ( 23251661)
Interacting Genes		1 interacting genes: UBE2I
Entrez ID		79400
HPRD ID		07359
Ensembl ID
Uniprot IDs		A3QRJ0 Q96PH1
PDB IDs		6SZ5 8U7Y 8U85 8U86 8U87
Enriched GO Terms of Interacting Partners?		RING-like Zinc Finger Domain Binding SUMO Ligase Complex HLH Domain Binding SUMO Conjugating Enzyme Activity Small Protein Activating Enzyme Binding Mitotic Nuclear Membrane Reassembly Transferase Complex Transcription Factor Binding SUMO Transferase Activity Presynaptic Cytosol Postsynaptic Cytosol Nuclear Membrane Reassembly Synaptonemal Complex Transcription Coregulator Binding Nuclear Membrane Organization Protein Sumoylation Membrane Assembly Nuclear Pore Schaffer Collateral - CA1 Synapse PML Body Nuclear Export Chromosome Segregation
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