BCL2L14

Description		BCL2 like 14
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Endomembrane System Membrane Intracellular Organelle
	Molecular Function	Protein Binding Protein Kinase Binding
	Biological Process	Apoptotic Process Regulation Of Apoptotic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163) Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Estimated glomerular filtration rate ( 31152163) Femur bone mineral density x serum urate levels interaction ( 34046847) Phosphorus levels ( 29403010) Voxel-wise structural brain imaging measurements in Alzheimer’s disease ( 30584014)
Interacting Genes		6 interacting genes: BCL2 BCL2L1 COPS5 DDIT4L PICK1 TEPSIN
Entrez ID		79370
HPRD ID		05841
Ensembl ID		ENSG00000121380
Uniprot IDs		Q9BZR8
PDB IDs
Enriched GO Terms of Interacting Partners?		Dendritic Cell Apoptotic Process BH3 Domain Binding Negative Regulation Of Dendritic Cell Apoptotic Process Bcl-2 Family Protein Complex Negative Regulation Of Anoikis Programmed Cell Death Involved In Cell Development Release Of Cytochrome C From Mitochondria Regulation Of Anoikis Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Channel Activity Epithelial Cell Apoptotic Process Ovarian Follicle Development Cellular Response To Glucose Starvation Leukocyte Apoptotic Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Response To Gamma Radiation Regulation Of Mitochondrial Membrane Permeability Negative Regulation Of Leukocyte Apoptotic Process Apoptotic Mitochondrial Changes Regulation Of Membrane Permeability Regulation Of Mitochondrial Membrane Potential Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Retinal Cell Programmed Cell Death Negative Regulation Of Cellular PH Reduction Apoptotic Process In Bone Marrow Cell Coated Vesicle Membrane Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Male Gonad Development Neuron Apoptotic Process Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Mitochondrial Membrane Organization CD8-positive, Alpha-beta T Cell Lineage Commitment Negative Regulation Of Autophagy BAD-BCL-2 Complex Channel Inhibitor Activity Regulation Of Cellular Response To Stress Trans-Golgi Network Membrane Macrophage Migration Inhibitory Factor Binding Negative Regulation Of Signaling Mononuclear Cell Proliferation Negative Regulation Of Cell Communication Cochlear Nucleus Development Gonad Development Cellular Response To Decreased Oxygen Levels Regulation Of Nitrogen Utilization Leukocyte Proliferation
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