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CHAC1

Name ChaC glutathione specific gamma-glutamylcyclotransferase 1
Structure No pdb structure
Interactors 1 interactors: RHOXF2
GO Annotations Cellular Component
  • Cytoplasm
  • Golgi Apparatus
  • Trans-Golgi Network
  • Cytosol
Molecular Function
  • Gamma-glutamylcyclotransferase Activity
  • Notch Binding
  • Protein Binding
  • Lyase Activity
  • Glutathione Specific Gamma-glutamylcyclotransferase Activity
Biological Process
  • Glutathione Biosynthetic Process
  • Glutathione Catabolic Process
  • Apoptotic Process
  • Response To Unfolded Protein
  • Notch Signaling Pathway
  • Nervous System Development
  • Negative Regulation Of Protein Processing
  • Neurogenesis
  • Negative Regulation Of Notch Signaling Pathway
  • Response To Caloric Restriction
  • Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Pathways
  • Glutathione synthesis and recycling
  • Response of EIF2AK1 (HRI) to heme deficiency
GWAS
  • FEV1 ( 30804560 )
  • Lung function (FVC) ( 30804560 )
  • Malaria ( 31844061 )
  • Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738 )
  • Waist circumference adjusted for body mass index ( 34021172 )
Entrez ID 79094
HPRD ID 14634
Ensembl ID ENSG00000128965
Uniprot IDs Q9BUX1
PDB IDs Not available

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