C2orf49

Name	chromosome 2 open reading frame 49
Structure	No pdb structure
Interactors	3 interactors: APP CEBPA TRIM54
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm TRNA-splicing Ligase Complex
	Molecular Function	Protein Binding
	Biological Process	TRNA Splicing, Via Endonucleolytic Cleavage And Ligation Embryonic Morphogenesis
Pathways	tRNA processing in the nucleus
GWAS	Body mass index ( 26426971 ) Smoking behaviour (cigarette pack-years) ( 30679032 )
Entrez ID	79074
HPRD ID	14688
Ensembl ID	ENSG00000135974
Uniprot IDs	C9J4K0 Q9BVC5
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Positive Regulation Of Proteolysis Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Inflammatory Response Regulation Of Response To Calcium Ion Developmental Maturation Amylin Binding Positive Regulation Of Protein Catabolic Process Endosome To Plasma Membrane Transport Vesicle Cell Maturation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Defense Response Lipoprotein Particle Memory Notch Signaling Pathway Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Cellular Response To Metal Ion CHOP-C/EBP Complex RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Learning Or Memory Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling White Fat Cell Proliferation Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Regulation Of Spontaneous Synaptic Transmission Cognition NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Response To Metal Ion