ST8SIA4

Gene Name		ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Integral Component Of Golgi Membrane
	Molecular Function	Alpha-N-acetylneuraminate Alpha-2,8-sialyltransferase Activity Sialic Acid Binding
	Biological Process	Ganglioside Biosynthetic Process Cellular Protein Modification Process Protein Glycosylation Dolichol-linked Oligosaccharide Biosynthetic Process N-glycan Processing Nervous System Development Axon Guidance Oligosaccharide Metabolic Process Protein N-linked Glycosylation Via Asparagine Post-translational Protein Modification Cellular Protein Metabolic Process Sialylation
Pathways		Diseases of glycosylation Axon guidance Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Defective MOGS causes MOGS-CDG (CDG-2b) Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 NCAM signaling for neurite out-growth Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) NCAM1 interactions Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Synthesis of substrates in N-glycan biosythesis Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Sialic acid metabolism Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Diseases associated with N-glycosylation of proteins
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: NCAM1
Entrez ID		7903
HPRD ID		03970
Ensembl ID		ENSG00000113532
Uniprot IDs		Q92187
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?		7mg appreciably became cannabinoids cannabis cognition consequence consisting delta9 dentate functionally genetically hit juvenile lasting ncam obvious outer plasticity polysialic polysialylation polysialyltransferases predisposed synergistic tetrahydrocannabinol thc variations wildtype