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ST8SIA4

Description ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
Image
GO Annotations Cellular Component
  • Golgi Membrane
  • Extracellular Region
  • Golgi Apparatus
  • Membrane
Molecular Function
  • Alpha-N-acetylneuraminate Alpha-2,8-sialyltransferase Activity
  • Sialyltransferase Activity
  • Transferase Activity
  • Glycosyltransferase Activity
  • Sialic Acid Binding
Biological Process
  • Ganglioside Biosynthetic Process
  • Protein Glycosylation
  • N-glycan Processing
  • Nervous System Development
  • Oligosaccharide Metabolic Process
  • Protein Modification Process
  • Sialylation
Pathways
  • Sialic acid metabolism
  • NCAM1 interactions
Drugs
Diseases
GWAS
  • Lymphocyte count ( 32888494)
  • Response to radiotherapy in cancer (late toxicity) ( 24785509)
  • Systemic lupus erythematosus ( 28714469 29848360 33272962 33493351)
  • Waist circumference adjusted for body mass index ( 28552196)
  • White blood cell count ( 32888494)
Interacting Genes 1 interacting genes: NCAM1
Entrez ID 7903
HPRD ID 03970
Ensembl ID ENSG00000113532
Uniprot IDs Q92187
PDB IDs 5Y22 5Y3U 6AHZ
Enriched GO Terms of Interacting Partners?
  • Regulation Of Semaphorin-plexin Signaling Pathway
  • Commissural Neuron Axon Guidance
  • Epithelial To Mesenchymal Transition
  • Mesenchymal Cell Differentiation
  • Symbiont Entry Into Host Cell
  • Side Of Membrane
  • Virus Receptor Activity
  • Biological Process Involved In Interaction With Host
  • Axon Guidance
  • Neuron Projection Guidance
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