TRIR

Description		telomerase RNA component interacting RNase
Image		No pdb structure
GO Annotations	Cellular Component
	Molecular Function	RNA Binding Nuclease Activity Exonuclease Activity Protein Binding 3'-5' Exonuclease Activity 5'-3' Exonuclease Activity Hydrolase Activity
	Biological Process	RRNA Catabolic Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes		4 interacting genes: APP CEBPA ERBB3 SNRPA
Entrez ID		79002
HPRD ID		14528
Ensembl ID		ENSG00000123144
Uniprot IDs		K7ELS0 K7EN60 Q9BQ61
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Inflammatory Response Regulation Of Response To Calcium Ion Positive Regulation Of Calcium-mediated Signaling Intracellular Signaling Cassette Amylin Binding Endosome To Plasma Membrane Transport Vesicle Cell Maturation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cell Development Regulation Of Calcium-mediated Signaling Protein Heterodimerization Activity Lipoprotein Particle Memory Notch Signaling Pathway Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Glial Cell Development Positive Regulation Of G Protein-coupled Receptor Internalization Cellular Response To Metal Ion Identical Protein Binding CHOP-C/EBP Complex RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Neuregulin Receptor Activity Positive Regulation Of Proteolysis Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Developmental Maturation Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Protein Catabolic Process Cellular Response To Norepinephrine Stimulus Receptor Complex Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling White Fat Cell Proliferation Spliceosomal SnRNP Complex Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition
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