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LRFN4

Description leucine rich repeat and fibronectin type III domain containing 4
Image No pdb structure
GO Annotations Cellular Component
  • Plasma Membrane
  • Cell Surface
  • Membrane
  • Postsynaptic Density Membrane
  • Glutamatergic Synapse
  • GABA-ergic Synapse
Molecular Function
  • Protein Binding
Biological Process
  • Regulation Of Postsynaptic Density Assembly
  • Synaptic Membrane Adhesion
  • Regulation Of Presynapse Assembly
Pathways
  • Synaptic adhesion-like molecules
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • Bipolar disorder ( 21926972 31043756)
Interacting Genes 10 interacting genes: ADAMTSL4 CFTR CYSRT1 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP6-2 NBPF19 NOTCH2NLA P4HB
Entrez ID 78999
HPRD ID 14310
Ensembl ID ENSG00000173621
Uniprot IDs Q6PJG9
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Intermediate Filament
  • Keratin Filament
  • Intracellularly ATP-gated Chloride Channel Activity
  • Positive Regulation Of Voltage-gated Chloride Channel Activity
  • Sec61 Translocon Complex Binding
  • Pigment Cell Development
  • Positive Regulation Of Anion Channel Activity
  • Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline
  • Procollagen-proline 4-dioxygenase Complex
  • Positive Regulation Of Monoatomic Anion Transport
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