COLEC11

Description		collectin subfamily member 11
Image
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space External Side Of Plasma Membrane Serine-type Endopeptidase Complex
	Molecular Function	DNA Binding Calcium Ion Binding Protein Binding D-mannose Binding Carbohydrate Binding Identical Protein Binding Fucose Binding Metal Ion Binding Oligosaccharide Binding Calcium-dependent Carbohydrate Binding
	Biological Process	Complement Activation, Lectin Pathway Immune System Process Cell Surface Pattern Recognition Receptor Signaling Pathway Proteolysis Complement Activation Antimicrobial Humoral Response Developmental Process Innate Immune Response Execution Phase Of Apoptosis Positive Regulation Of Opsonization
Pathways		Lectin pathway of complement activation Initial triggering of complement Scavenging by Class A Receptors
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Appendicular lean mass ( 33097823) Chronic kidney disease (reduced eGFR or end stage renal disease) in type 1 diabetes ( 31537649) Diastolic blood pressure ( 30224653) Fibrinogen levels ( 26561523) HDL cholesterol levels ( 32203549) Intraocular pressure ( 30591961) LDL cholesterol levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Pre-treatment viral load in HIV-1 infection ( 31219150) Serum alkaline phosphatase levels ( 33547301) Triglyceride levels ( 32203549)
Interacting Genes		1 interacting genes: SNCA
Entrez ID		78989
HPRD ID		10847
Ensembl ID		ENSG00000118004
Uniprot IDs		Q9BWP8
PDB IDs		4YLI 4YMD
Enriched GO Terms of Interacting Partners?		Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Catecholamine Metabolic Process Dopamine Uptake Involved In Synaptic Transmission Mitochondrial ATP Synthesis Coupled Electron Transport Cuprous Ion Binding Regulation Of Chaperone-mediated Autophagy Response To Iron(II) Ion Dopamine Biosynthetic Process Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Cellular Respiration Negative Regulation Of Oxidative Phosphorylation Regulation Of Acyl-CoA Biosynthetic Process Supramolecular Fiber Catecholamine Uptake Dopamine Uptake Positive Regulation Of Inositol Phosphate Biosynthetic Process SNARE Complex Assembly Cellular Response To Epinephrine Stimulus Regulation Of SNARE Complex Assembly Negative Regulation Of Microtubule Polymerization Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway ATP Synthesis Coupled Electron Transport Positive Regulation Of Receptor Recycling Synaptic Transmission, Dopaminergic Response To Epinephrine Positive Regulation Of Neurotransmitter Secretion Regulation Of Hydrogen Peroxide Metabolic Process Platelet Alpha Granule Membrane Dynein Complex Binding Synaptic Vesicle Priming Dopamine Transport Inclusion Body Neurotransmitter Reuptake Catecholamine Biosynthetic Process Response To Magnesium Ion Behavioral Response To Cocaine Phospholipase Binding
Tagcloud ?