SLC30A1

Name	solute carrier family 30 member 1
Structure
Novel Interactors	1 novel interactors: CENPF
Interactors	2 interactors: MTNR1A MTNR1B
GO Annotations	Cellular Component	Golgi Membrane Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane Basolateral Plasma Membrane T-tubule Dendrite Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Nuclear Membrane Schaffer Collateral - CA1 Synapse Postsynaptic Density Membrane Postsynaptic Density, Intracellular Component Glutamatergic Postsynaptic Density
	Molecular Function	Zinc Ion Transmembrane Transporter Activity Protein Binding Monoatomic Cation Transmembrane Transporter Activity Antiporter Activity Calcium Channel Inhibitor Activity Metal Ion Binding Zinc:proton Antiporter Activity
	Biological Process	In Utero Embryonic Development Monoatomic Ion Transport Monoatomic Cation Transport Zinc Ion Transport Intracellular Calcium Ion Homeostasis Intracellular Zinc Ion Homeostasis Detoxification Of Zinc Ion Defense Response To Bacterium Negative Regulation Of Neurotransmitter Secretion Transmembrane Transport Positive Regulation Of Dendritic Spine Morphogenesis Zinc Ion Import Into Organelle Calcium Ion Import Cadmium Ion Transmembrane Transport Zinc Ion Transmembrane Transport Negative Regulation Of Zinc Ion Transmembrane Import Detoxification Of Cadmium Ion Negative Regulation Of Calcium Ion Import Zinc Export Across Plasma Membrane Regulation Of Postsynaptic Density Protein 95 Clustering
Pathways	Zinc efflux and compartmentalization by the SLC30 family
GWAS	Appendicular lean mass ( 33097823 ) Hypertension ( 21347282 ) Nevus count ( 33959940 ) Serum alkaline phosphatase levels ( 33547301 )
Entrez ID	7779
HPRD ID	15366
Ensembl ID	ENSG00000170385
Uniprot IDs	Q9Y6M5
PDB IDs	8J2G 8XM6 8XMA 8XMF 8XMJ 8ZB0 8ZSB 8ZSZ
GO Terms Enriched among Interactors ?	Melatonin Receptor Activity G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Ciliary Transition Fiber Pronucleus G Protein-coupled Receptor Activity Positive Regulation Of Transmission Of Nerve Impulse Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of CGMP-mediated Signaling Regulation Of Neuronal Action Potential Negative Regulation Of Transmission Of Nerve Impulse Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Kinetochore Assembly Outer Kinetochore Dynein Complex Binding Ventricular System Development Kinetochore Organization Mating Behavior Hormone Binding Positive Regulation Of Circadian Rhythm Negative Regulation Of Nervous System Process Regulation Of Transmission Of Nerve Impulse Negative Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Vasoconstriction Regulation Of CGMP-mediated Signaling Regulation Of Circadian Sleep/wake Cycle, Sleep Regulation Of Circadian Sleep/wake Cycle Mitotic Spindle Assembly Checkpoint Signaling Negative Regulation Of Mitotic Metaphase/anaphase Transition Reproductive Behavior G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Behavior Regulation Of Striated Muscle Tissue Development Negative Regulation Of Mitotic Nuclear Division Negative Regulation Of Insulin Secretion Regulation Of Muscle Organ Development Negative Regulation Of Peptide Secretion