CA7

Name	carbonic anhydrase 7
Structure
Novel Interactors	2 novel interactors: CDH5 FADS2
Interactors	None recorded
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Carbonate Dehydratase Activity Zinc Ion Binding Lyase Activity Metal Ion Binding
	Biological Process	Positive Regulation Of Synaptic Transmission, GABAergic Positive Regulation Of Cellular PH Reduction Regulation Of Intracellular PH Neuron Cellular Homeostasis Regulation Of Chloride Transport
Pathways	Reversible hydration of carbon dioxide
Drugs	Ethoxzolamide Benzthiazide Cyclothiazide Methazolamide Hydroflumethiazide Acetazolamide Zonisamide Diclofenamide Ellagic acid
GWAS	No GWAS studies recorded
Entrez ID	766
HPRD ID	00263
Ensembl ID	ENSG00000168748
Uniprot IDs	P43166
PDB IDs	3MDZ 3ML5 6G4T 6H36 6H37 6H38 6SDT 6ZR9 7NC4 7P1A 8Q3U
GO Terms Enriched among Interactors ?	Positive Regulation Of Establishment Of Endothelial Barrier Protein Localization To Bicellular Tight Junction Blood Vessel Maturation Fibrinogen Binding Positive Regulation Of Cellular Response To Oxidative Stress Arachidonate Metabolite Production Involved In Inflammatory Response Positive Regulation Of Response To Oxidative Stress Acyl-CoA 6-desaturase Activity Acyl-CoA Desaturase Activity Oxidoreductase Activity, Acting On Paired Donors, With Oxidation Of A Pair Of Donors Resulting In The Reduction Of Molecular Oxygen To Two Molecules Of Water Stearoyl-CoA 9-desaturase Activity Vascular Endothelial Growth Factor Receptor 2 Binding Endothelial Cell Morphogenesis Negative Regulation Of Microtubule Polymerization BMP Receptor Binding Production Of Molecular Mediator Involved In Inflammatory Response Alpha-linolenic Acid Metabolic Process Protein Localization To Cell-cell Junction Regulation Of Establishment Of Endothelial Barrier Regulation Of Cellular Response To Oxidative Stress Linoleic Acid Metabolic Process Regulation Of Establishment Of Cell Polarity Cell Migration Involved In Sprouting Angiogenesis Regulation Of Establishment Or Maintenance Of Cell Polarity Signaling Receptor Complex Adaptor Activity Regulation Of Endothelial Cell Differentiation Blood Vessel Endothelial Cell Migration Negative Regulation Of Endothelial Cell Apoptotic Process Cell-cell Adhesion Mediator Activity Cell-cell Adhesion Mediated By Cadherin Catenin Complex Maintenance Of Blood-brain Barrier Epithelial Cell Morphogenesis Protein Tyrosine Kinase Binding Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of BMP Signaling Pathway Regulation Of Response To Oxidative Stress Long-chain Fatty Acid Biosynthetic Process Unsaturated Fatty Acid Biosynthetic Process Bicellular Tight Junction Assembly Negative Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Vascular Permeability Tight Junction Assembly Adherens Junction Organization Fatty Acid Derivative Biosynthetic Process Tight Junction Organization Regulation Of Endothelial Cell Apoptotic Process Regulation Of Microtubule Polymerization Fatty Acid Derivative Metabolic Process Protein Localization To Cell Junction