ZKSCAN1

Name	zinc finger with KRAB and SCAN domains 1
Structure	No pdb structure
Novel Interactors	1 novel interactors: DYNC1I1
Interactors	2 interactors: APP MAPK7
GO Annotations	Cellular Component	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways	Generic Transcription Pathway
GWAS	Brain morphology (MOSTest) ( 32665545 ) Chronic obstructive pulmonary disease ( 30804561 ) Diastolic blood pressure ( 27841878 ) Height ( 31562340 ) Hemoglobin levels ( 32327693 ) Lung function (FEV1/FVC) ( 28166213 30804560 ) Refractive error ( 32231278 ) Subcortical volume (MOSTest) ( 32665545 ) Ticagrelor levels in individuals with acute coronary syndromes treated with ticagrelor ( 25935875 )
Entrez ID	7586
HPRD ID	03161
Ensembl ID	ENSG00000106261
Uniprot IDs	B3KNP9 B3KRF7 E9PC66 P17029
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Regulation Of Extrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Cytoskeleton-dependent Intracellular Transport Regulation Of Response To Calcium Ion Calcium-mediated Signaling Recycling Endosome Microtubule-based Transport Transport Along Microtubule Amylin Binding Regulation Of Intrinsic Apoptotic Signaling Pathway Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Calcium-mediated Signaling Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Growth Factor Stimulus Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Response To Growth Factor Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Dynein Light Chain Binding Peptidase Activator Activity Cellular Response To Manganese Ion Regulation Of Apoptotic Signaling Pathway