WNT2B

Gene Name		wingless-type MMTV integration site family, member 2B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space
	Molecular Function	Frizzled Binding
	Biological Process	Chondrocyte Differentiation Lens Development In Camera-type Eye Male Gonad Development Cellular Response To Starvation Wnt Signaling Pathway Forebrain Regionalization Neuron Differentiation Cell Fate Commitment Canonical Wnt Signaling Pathway Lung Induction Mesenchymal-epithelial Cell Signaling Iris Morphogenesis Cornea Development In Camera-type Eye Hematopoietic Stem Cell Proliferation Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR WNT ligand secretion is abrogated by the PORCN inhibitor LGK974 Signaling by Wnt Signaling by WNT in cancer Metabolic disorders of biological oxidation enzymes GPCR ligand binding WNT ligand biogenesis and trafficking Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: BRCA1 RAD21
Entrez ID		7482
HPRD ID		03574
Ensembl ID
Uniprot IDs		Q5TEH9 Q93097
PDB IDs
Enriched GO Terms of Interacting Partners?		Double-strand Break Repair Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Chromosome Segregation DNA Recombination Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Cellular Response To Indole-3-methanol Negative Regulation Of Centriole Replication Dosage Compensation By Inactivation Of X Chromosome Protein K6-linked Ubiquitination DNA Repair Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation Protein Localization To Chromatin Regulation Of Histone H4 Acetylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Negative Regulation Of Fatty Acid Biosynthetic Process DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Histone Methylation Cellular Response To DNA Damage Stimulus Negative Regulation Of Centrosome Duplication Regulation Of DNA Methylation Negative Regulation Of Histone Acetylation Positive Regulation Of Histone Acetylation Negative Regulation Of Peptidyl-lysine Acetylation Regulation Of Histone H3-K4 Methylation Negative Regulation Of Protein Acetylation Positive Regulation Of Peptidyl-lysine Acetylation Apoptotic Process Positive Regulation Of Protein Acetylation Postreplication Repair Regulation Of Transcription From RNA Polymerase III Promoter Programmed Cell Death Negative Regulation Of Fatty Acid Metabolic Process Cell Cycle Process Regulation Of Gene Expression By Genetic Imprinting DNA Metabolic Process Cell Death Death Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Protein Localization To Chromosome Genetic Imprinting Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Vascular Endothelial Growth Factor Production
Tagcloud ?		acta2 amscs architectural cd105 cd73 cd90 chondrogenic confluence confluent cyto eng fibroblastic hinfp nes npat nt5e pou5f1 renewing rnaseq sfrp2 sfrp4 successively thy1 versatility wisp2 wnt5a wnt5b wnt7b