WNT8A

Gene Name		wingless-type MMTV integration site family, member 8A
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space
	Molecular Function	Frizzled Binding Receptor Agonist Activity
	Biological Process	Neural Crest Cell Fate Commitment Neuron Differentiation Response To Retinoic Acid Regulation Of Transcription Involved In Anterior/posterior Axis Specification Canonical Wnt Signaling Pathway Involved In Neural Crest Cell Differentiation Palate Development Canonical Wnt Signaling Pathway Canonical Wnt Signaling Pathway Involved In Cardiac Muscle Cell Fate Commitment Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling Signaling by Wnt GPCR ligand binding Metabolic disorders of biological oxidation enzymes WNT ligand biogenesis and trafficking disassembly of the destruction complex and recruitment of AXIN to the membrane WNT ligand secretion is abrogated by the PORCN inhibitor LGK974 TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN Signaling by WNT in cancer Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS		Atrial fibrillation ( 22544366)
Protein-protein Interactions		1 interactors: LNX1
Entrez ID		7478
HPRD ID		05898
Ensembl ID		ENSG00000061492
Uniprot IDs		D6RF47 Q9H1J5
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?		a2ml altogether bmp chordin codon concerted embryogenesis epcam gsk3a head headless intron junction knocked microarrays morphogenetic morpholino morpholinos otx2 patterning rbm47 rescued splice start stranded trunk vertebrate zebrafish