VEGFC

Gene Name		vascular endothelial growth factor C
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Membrane Platelet Alpha Granule Lumen
	Molecular Function	Protein Binding Growth Factor Activity Chemoattractant Activity Vascular Endothelial Growth Factor Receptor 3 Binding
	Biological Process	Angiogenesis Positive Regulation Of Cell-matrix Adhesion Positive Regulation Of Neuroblast Proliferation Platelet Degranulation Substrate-dependent Cell Migration Signal Transduction Blood Coagulation Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Organ Morphogenesis Morphogenesis Of Embryonic Epithelium Platelet Activation Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Autophosphorylation Response To Drug Positive Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Angiogenesis Negative Regulation Of Blood Pressure Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of Protein Secretion Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Chemotaxis Induction Of Positive Chemotaxis Positive Regulation Of Cell Division Positive Regulation Of Mast Cell Chemotaxis Positive Regulation Of Lymphangiogenesis
Pathways		VEGF binds to VEGFR leading to receptor dimerization VEGF ligand-receptor interactions Signaling by VEGF Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS		HIV-1 viral setpoint ( 22174851)
Protein-protein Interactions		2 interactors: FLT4 KDR
Entrez ID		7424
HPRD ID		03317
Ensembl ID		ENSG00000150630
Uniprot IDs		P49767
PDB IDs		2X1W 2X1X 4BSK
Enriched GO Terms of Interacting Partners?		Lymph Vessel Development Vascular Endothelial Growth Factor Signaling Pathway Cellular Response To Vascular Endothelial Growth Factor Stimulus Sprouting Angiogenesis Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Endothelial Cell Proliferation Positive Regulation Of Epithelial Cell Migration Regulation Of Endothelial Cell Proliferation Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Endothelial Cell Migration Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Epithelial Cell Migration Positive Regulation Of Epithelial Cell Proliferation Regulation Of ERK1 And ERK2 Cascade Protein Autophosphorylation Peptidyl-tyrosine Phosphorylation Regulation Of Epithelial Cell Proliferation Positive Regulation Of Cell Migration Angiogenesis Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Blood Vessel Morphogenesis Positive Regulation Of MAPK Cascade Regulation Of Blood Vessel Remodeling Blood Vessel Development Vasculature Development Cellular Response To Growth Factor Stimulus Regulation Of Cell Migration Response To Growth Factor Regulation Of MAPK Cascade Regulation Of Cell Motility Positive Regulation Of Protein Kinase C Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Locomotion Regulation Of Cellular Component Movement Lymphangiogenesis Positive Regulation Of Protein Phosphorylation Surfactant Homeostasis Lymph Vessel Morphogenesis Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of Vasculogenesis Chemical Homeostasis Within A Tissue Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Proliferation Positive Regulation Of Phosphorylation Regulation Of Vasculogenesis Cardiovascular System Development Regulation Of Protein Kinase C Signaling
Tagcloud ?		adam19 adamts16 adamts9 aggf1 altitude altitudes ccbe1 creld1 dahe dhp dwells f2rl1 fgf10 fgf5 foxm gdap1 gna14 involvements jmjd1c nrbf2 parp8 pla2g4a rhog rtel1 sweeps vps13a wuzhishan wzsp zfpm2