UGT8

Description		UDP glycosyltransferase 8
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	N-acylsphingosine Galactosyltransferase Activity UDP-glycosyltransferase Activity UDP-galactose:glucosylceramide Beta-1,4-galactosyltransferase Activity Transferase Activity Glycosyltransferase Activity Hexosyltransferase Activity
	Biological Process	Protein Localization To Paranode Region Of Axon Lipid Metabolic Process Sphingolipid Metabolic Process Galactosylceramide Biosynthetic Process Glycosphingolipid Biosynthetic Process Cytoskeleton Organization Nervous System Development Central Nervous System Development Peripheral Nervous System Development Glycolipid Biosynthetic Process Paranodal Junction Assembly Response To Immobilization Stress Neuron Projection Morphogenesis
Pathways		Glycosphingolipid biosynthesis
Drugs
Diseases
GWAS		Body fat mass ( 28552196) Estimated glomerular filtration rate ( 31152163) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Metabolite levels ( 23823483) Optic disc area ( 28073927) Red blood cell count ( 32888494)
Interacting Genes		2 interacting genes: ADRA1A AGTR1
Entrez ID		7368
HPRD ID		03186
Ensembl ID		ENSG00000174607
Uniprot IDs		Q16880
PDB IDs
Enriched GO Terms of Interacting Partners?		Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Blood Vessel Diameter Maintenance Negative Regulation Of Heart Rate Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Regulation Of Blood Pressure Regulation Of Tube Size Regulation Of Vasoconstriction Angiotensin Type I Receptor Activity Regulation Of Blood Circulation Positive Regulation Of The Force Of Heart Contraction By Epinephrine-norepinephrine Positive Regulation Of Heart Rate By Epinephrine-norepinephrine Vascular Process In Circulatory System Phospholipase C-activating Adrenergic Receptor Signaling Pathway Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Bradykinin Receptor Binding Pilomotor Reflex Alpha1-adrenergic Receptor Activity Circulatory System Process Positive Regulation Of The Force Of Heart Contraction By Chemical Signal Phospholipase C-activating Angiotensin-activated Signaling Pathway Renin-angiotensin Regulation Of Aldosterone Production Protein Heterodimerization Activity G Protein-coupled Receptor Activity Angiotensin Type II Receptor Activity Neuron-glial Cell Signaling Maintenance Of Blood Vessel Diameter Homeostasis By Renin-angiotensin Regulation Of The Force Of Heart Contraction By Chemical Signal Positive Regulation Of Cardiac Muscle Contraction Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of System Process Positive Regulation Of Action Potential Adrenergic Receptor Activity Regulation Of Renal Sodium Excretion Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Negative Regulation Of Heart Rate Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Adult Heart Development Positive Regulation Of Striated Muscle Contraction Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Positive Regulation Of Synaptic Transmission, GABAergic Low-density Lipoprotein Particle Remodeling G Protein-coupled Receptor Signaling Pathway Reflex Positive Regulation Of Macrophage Derived Foam Cell Differentiation Angiotensin-activated Signaling Pathway Renal System Process Involved In Regulation Of Systemic Arterial Blood Pressure Intracellular Signaling Cassette Adrenergic Receptor Signaling Pathway Negative Regulation Of Heart Contraction Negative Regulation Of Blood Circulation
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