UGT2B4

Gene Name		UDP glucuronosyltransferase 2 family, polypeptide B4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Retinoic Acid Binding Glucuronosyltransferase Activity
	Biological Process	Estrogen Catabolic Process Xenobiotic Metabolic Process Metabolic Process Flavonoid Biosynthetic Process Cellular Response To Hormone Stimulus Cellular Glucuronidation Flavonoid Glucuronidation
Pathways		Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective UGT1A4 causes hyperbilirubinemia Metabolic disorders of biological oxidation enzymes Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Glucuronidation Biological oxidations Defective GGT1 causes Glutathionuria (GLUTH) Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: STAT5A
Entrez ID		7363
HPRD ID		02507
Ensembl ID		ENSG00000156096
Uniprot IDs		A6NCP7 G5E9X8 P06133
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mast Cell Differentiation Regulation Of Mast Cell Differentiation Development Of Secondary Male Sexual Characteristics Negative Regulation Of Mast Cell Apoptotic Process Creatinine Metabolic Process Regulation Of Mast Cell Apoptotic Process Positive Regulation Of Mast Cell Proliferation Isoleucine Metabolic Process Allantoin Metabolic Process Taurine Metabolic Process Positive Regulation Of Gamma-delta T Cell Differentiation Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Negative Regulation Of Erythrocyte Differentiation Prolactin Signaling Pathway Positive Regulation Of Gamma-delta T Cell Activation Development Of Secondary Female Sexual Characteristics Valine Metabolic Process Creatine Metabolic Process Positive Regulation Of Natural Killer Cell Differentiation Succinate Metabolic Process Regulation Of Gamma-delta T Cell Differentiation Development Of Secondary Sexual Characteristics Luteinization Positive Regulation Of Interleukin-2 Biosynthetic Process Positive Regulation Of B Cell Differentiation 2-oxoglutarate Metabolic Process Peyer's Patch Development Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Epithelial Cell Differentiation Involved In Prostate Gland Development Oxaloacetate Metabolic Process Negative Regulation Of Myeloid Cell Apoptotic Process Positive Regulation Of Natural Killer Cell Mediated Immunity Natural Killer Cell Differentiation Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Activated T Cell Proliferation JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Interleukin-2 Biosynthetic Process Positive Regulation Of Natural Killer Cell Activation Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus Regulation Of B Cell Differentiation Positive Regulation Of Interleukin-2 Production Regulation Of Erythrocyte Differentiation Regulation Of Activated T Cell Proliferation T Cell Homeostasis Regulation Of Myeloid Cell Apoptotic Process Lipid Storage Prostate Gland Epithelium Morphogenesis Response To Growth Hormone
Tagcloud ?		accounting car cnv discover esr1 fdr genotyped glucuronidation glucuronosyltransferases livers pharmacogenetic pxr quantified tagsnps tfs udp ugt1a ugt1a1 ugt1a3 ugt1a4 ugt1a6 ugt1a9 ugts