TUB

Description		TUB bipartite transcription factor
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Cytosol Plasma Membrane Cilium Membrane
	Molecular Function	G Protein-coupled Receptor Binding Protein-containing Complex Binding Intraciliary Transport Particle A Binding
	Biological Process	Phagocytosis Phagocytosis, Recognition Sensory Perception Of Sound Regulation Of G Protein-coupled Receptor Signaling Pathway Intraciliary Transport Photoreceptor Cell Maintenance Positive Regulation Of Phagocytosis Retina Development In Camera-type Eye Protein Localization To Cilium Receptor Localization To Non-motile Cilium Protein Localization To Photoreceptor Outer Segment
Pathways
Drugs		(1R,2R,3S,4R,6S)-3,4,6-Trihydroxy-5-{[(S)-hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-1,2-cyclohexanediyl bis[dihydrogen (phosphate)]
Diseases
GWAS		Age-related hearing impairment ( 34108613) Body mass index ( 20935630 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Coronary artery disease in type 1 diabetes ( 29695241) Familial lung adenocarcinoma ( 29924316) Familial lung cancer ( 29924316) Malaria ( 31844061)
Interacting Genes		9 interacting genes: ABL1 GNAQ GRB2 IRS1 JAK2 LCK PIK3R1 PLCG1 SRC
Entrez ID		7275
HPRD ID		03121
Ensembl ID		ENSG00000166402
Uniprot IDs		P50607
PDB IDs		1S31
Enriched GO Terms of Interacting Partners?		Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway SH2 Domain Binding Phosphotyrosine Residue Binding Enzyme-linked Receptor Protein Signaling Pathway Phosphatidylinositol 3-kinase Binding Neurotrophin TRKA Receptor Binding Cell Surface Receptor Signaling Pathway Non-membrane Spanning Protein Tyrosine Kinase Activity Fc Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Insulin Receptor Substrate Binding ERBB Signaling Pathway Regulation Of Immune Response Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Immune System Process Leukocyte Activation Positive Regulation Of T Cell Activation Intracellular Signal Transduction Positive Regulation Of Leukocyte Cell-cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway T Cell Activation Regulation Of Cell Activation Cell Activation Positive Regulation Of Immune Response Ephrin Receptor Binding Positive Regulation Of Cell-cell Adhesion Positive Regulation Of Lymphocyte Activation Protein Tyrosine Kinase Activity Immune Response-activating Signaling Pathway Insulin-like Growth Factor Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Regulation Of Cell Adhesion Regulation Of T Cell Activation T Cell Differentiation Positive Regulation Of Cell Activation Regulation Of Leukocyte Cell-cell Adhesion Antigen Receptor-mediated Signaling Pathway Immune Effector Process Leukocyte Activation Involved In Immune Response Cell Activation Involved In Immune Response Immune Response-regulating Signaling Pathway Activation Of Immune Response Protein Kinase Binding T Cell Costimulation Substrate Adhesion-dependent Cell Spreading Lymphocyte Activation Regulation Of Immune System Process Peptidyl-tyrosine Phosphorylation B Cell Receptor Signaling Pathway
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