NR2E1

Gene Name		nuclear receptor subfamily 2, group E, member 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Steroid Hormone Receptor Activity Zinc Ion Binding Histone Deacetylase Binding Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Behavioral Fear Response Aggressive Behavior Transcription Initiation From RNA Polymerase II Promoter Nervous System Development Visual Perception Glial Cell Migration Gene Expression Dentate Gyrus Development Amygdala Development Olfactory Bulb Development Layer Formation In Cerebral Cortex Forebrain Generation Of Neurons Cerebral Cortex Neuron Differentiation Anterior Commissure Morphogenesis Extracellular Matrix Organization Somatic Stem Cell Maintenance Social Behavior Negative Regulation Of Apoptotic Process Steroid Hormone Mediated Signaling Pathway Cell Fate Commitment Negative Regulation Of Neuron Differentiation Positive Regulation Of Angiogenesis Positive Regulation Of Cell Cycle Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Astrocyte Differentiation Regulation Of Dendrite Morphogenesis Retina Development In Camera-type Eye Regulation Of Timing Of Neuron Differentiation Long-term Synaptic Potentiation Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Neural Precursor Cell Proliferation Positive Regulation Of Neural Precursor Cell Proliferation Positive Regulation Of Stem Cell Proliferation
Pathways		Generic Transcription Pathway Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: ATN1 BCL11A ERBB2IP KDM1A NSD1 RERE
Entrez ID		7101
HPRD ID		07230
Ensembl ID		ENSG00000112333
Uniprot IDs		B6ZGT9 Q6ZMP8 Q9Y466
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process RNA Metabolic Process Regulation Of Primitive Erythrocyte Differentiation Chromatin Modification Gene Expression Cellular Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Basal Protein Localization Chromatin Organization Negative Regulation Of Cellular Metabolic Process Establishment Or Maintenance Of Cell Polarity Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Protein Homooligomerization Chromosome Organization Multicellular Organismal Development Negative Regulation Of Collateral Sprouting Peptidyl-lysine Modification Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Protein Oligomerization Positive Regulation Of Megakaryocyte Differentiation Histone H3-K36 Methylation Leukocyte Differentiation Positive Regulation Of Collateral Sprouting Positive Regulation Of Hormone Biosynthetic Process Maintenance Of Cell Polarity Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Developmental Process
Tagcloud ?		carcinogenesis cdkn1a doxorubicin druggable ectopic enhancement escape exact oncogene orphan overcoming perform potently premalignant prevent promoted prostate prostatic pten rasg12v repression senescence sirt1 suppressing tlx transactivation triggered tumour tumourigenesis