TBXAS1

Description		thromboxane A synthase 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane
	Molecular Function	Monooxygenase Activity Thromboxane-A Synthase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Lyase Activity Isomerase Activity Heme Binding 12-hydroxyheptadecatrienoic Acid Synthase Activity Metal Ion Binding Hydroperoxy Icosatetraenoate Dehydratase Activity
	Biological Process	Prostaglandin Biosynthetic Process Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Icosanoid Metabolic Process Prostaglandin Metabolic Process Intracellular Chloride Ion Homeostasis Response To Ethanol Positive Regulation Of Vasoconstriction Prostanoid Biosynthetic Process Response To Fatty Acid
Pathways		Eicosanoids Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Defective TBXAS1 causes GHDD
Drugs		Ridogrel Dazoxiben NM-702
Diseases		Diaphyseal dysplasia with anemia (Ghosal)
GWAS		Acute lymphoblastic leukemia (childhood) ( 23007406) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Cerebellum growth ( 29682794) Cervical cancer ( 28806749) Coronary artery disease ( 29212778 33020668) Gray matter volume (schizophrenia interaction) ( 24086445) Heel bone mineral density ( 30598549) Height ( 31217584) Late-onset Alzheimer's disease ( 27770636) Myocardial infarction ( 33532862) Obesity-related traits ( 23251661) Systolic blood pressure ( 30578418) White blood cell count ( 32888494)
Interacting Genes		1 interacting genes: UBC
Entrez ID		6916
HPRD ID		02035
Ensembl ID		ENSG00000059377
Uniprot IDs		A0A498U6I9 B4DVP1 P24557
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Tag Activity
Tagcloud ?