TAT

Description		tyrosine aminotransferase
Image
GO Annotations	Cellular Component	Cellular_component Cytosol
	Molecular Function	Catalytic Activity L-tyrosine-2-oxoglutarate Transaminase Activity Protein Binding Transaminase Activity Amino Acid Binding Transferase Activity Pyridoxal Phosphate Binding Identical Protein Binding
	Biological Process	2-oxoglutarate Metabolic Process Amino Acid Metabolic Process Glutamate Metabolic Process L-phenylalanine Catabolic Process L-tyrosine Catabolic Process Response To Oxidative Stress Aromatic Amino Acid Metabolic Process Aromatic Amino Acid Family Catabolic Process Response To Mercury Ion Response To Glucocorticoid Response To Dexamethasone
Pathways		Tyrosine catabolism
Drugs		Pyridoxal phosphate Phenylalanine Tyrosine Glutamic acid
Diseases		Tyrosinemia; Tyrosinemia, type I; Tyrosinemia, type II; Tyrosinemia, type III; Hawkinsinuria
GWAS		Chronotype ( 30696823) Metabolite levels ( 22286219 22916037) Morning person ( 30696823) Urate levels ( 31578528)
Interacting Genes		3 interacting genes: GLUL GRN UBE3A
Entrez ID		6898
HPRD ID		11776
Ensembl ID		ENSG00000198650
Uniprot IDs		A0A140VKB7 P17735
PDB IDs		3DYD
Enriched GO Terms of Interacting Partners?		Intracellular Chemical Homeostasis Intracellular PH Reduction Cellular Homeostasis Regulation Of Cellular PH Regulation Of Intracellular PH Intracellular Ammonium Homeostasis Chemical Homeostasis Positive Regulation Of Aspartic-type Peptidase Activity Regulation Of PH Sperm Entry Positive Regulation Of Golgi Lumen Acidification Glutamine Synthetase Activity Glutamine Biosynthetic Process Positive Regulation Of Trophectodermal Cell Proliferation Regulation Of Endothelial Cell Migration Homeostatic Process Positive Regulation Of Inflammatory Response To Wounding Positive Regulation Of Protein Folding Regulation Of Golgi Lumen Acidification Cellular Response To Nutrient Levels Positive Regulation Of Lysosome Organization Astrocyte Activation Involved In Immune Response Trophectodermal Cell Proliferation Microglial Cell Activation Involved In Immune Response Negative Regulation Of Respiratory Burst Involved In Inflammatory Response Positive Regulation Of Cellular PH Reduction Ammonium Homeostasis Regulation Of Angiogenesis Negative Regulation Of Respiratory Burst Positive Regulation Of Protein Localization To Lysosome Regulation Of Vasculature Development L-glutamate Catabolic Process Catabolic Process Negative Regulation Of Neutrophil Activation Negative Regulation Of Microglial Cell Activation Regulation Of Respiratory Burst Involved In Inflammatory Response Cerebellar Climbing Fiber To Purkinje Cell Synapse Regulation Of Proteolysis Positive Regulation Of Axon Regeneration Intracellular Monoatomic Cation Homeostasis Regulation Of Protein Folding Intracellular Monoatomic Ion Homeostasis Prostate Gland Growth Regulation Of Protein Localization To Nucleolus Regulation Of Neutrophil Activation Positive Regulation Of Peptidase Activity Positive Regulation Of Defense Response To Bacterium Progesterone Receptor Signaling Pathway Response To Nutrient Levels Monoatomic Ion Homeostasis
Tagcloud ?