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SULT1A2
Gene Name
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
Image
Gene Ontology Annotations
Cellular Component
Cytosol
Molecular Function
Aryl Sulfotransferase Activity
Sulfotransferase Activity
Flavonol 3-sulfotransferase Activity
Biological Process
Catecholamine Metabolic Process
Xenobiotic Metabolic Process
Steroid Metabolic Process
Amine Biosynthetic Process
Phenol-containing Compound Metabolic Process
Small Molecule Metabolic Process
3'-phosphoadenosine 5'-phosphosulfate Metabolic Process
Sulfation
Pathways
Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)
Defective UGT1A4 causes hyperbilirubinemia
Metabolic disorders of biological oxidation enzymes
Phase II conjugation
Defective UGT1A1 causes hyperbilirubinemia
Cytosolic sulfonation of small molecules
Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)
Biological oxidations
Defective GGT1 causes Glutathionuria (GLUTH)
Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)
Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Diseases
GWAS
Body mass index (
20935630
)
Inflammatory bowel disease (
23128233
)
Inflammatory bowel disease (early onset) (
19915574
)
Protein-protein Interactions
1 interactors:
NIF3L1
Entrez ID
6799
HPRD ID
03187
Ensembl ID
ENSG00000197165
Uniprot IDs
P50226
PDB IDs
1Z29
Enriched GO Terms of Interacting Partners
?
7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process
Dihydrobiopterin Metabolic Process
Pteridine-containing Compound Biosynthetic Process
Pteridine-containing Compound Metabolic Process
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