STC1

Description		stanniocalcin 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytoplasm Apical Plasma Membrane
	Molecular Function	Hormone Activity Protein Binding Identical Protein Binding
	Biological Process	Ossification Endothelial Cell Morphogenesis Growth Plate Cartilage Axis Specification Intracellular Calcium Ion Homeostasis Signal Transduction Embryo Implantation Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Cell Migration Response To Vitamin D Chondrocyte Proliferation Regulation Of Monoatomic Anion Transport Decidualization Negative Regulation Of Calcium Ion Transport Bone Development Cellular Response To CAMP Cellular Response To Glucocorticoid Stimulus Cellular Response To Hypoxia Regulation Of Cardiac Muscle Cell Contraction Positive Regulation Of Calcium Ion Import Negative Regulation Of Renal Phosphate Excretion
Pathways
Drugs
Diseases
GWAS		Blood osmolality (transformed sodium) ( 28360221) Blood urea nitrogen levels ( 31152163 29403010) Chronic kidney disease ( 20383146 31152163) Creatinine levels ( 29403010 31015462) Estimated glomerular filtration rate ( 31152163 31451708 30604766 31015462) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate ( 27588450 29403010) Glomerular filtration rate (creatinine) ( 26831199 28452372) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Kidney volume ( 34128465) Serum uric acid levels ( 30993211) Subcutaneous adipose tissue ( 22589738) Urate levels ( 23263486 31578528 31985003) Urinary albumin-to-creatinine ratio ( 31511532) Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Novel Interacting Genes		1 novel interacting genes: MAT2B
Interacting Genes		2 interacting genes: MEOX2 NOTCH1
Entrez ID		6781
HPRD ID		03115
Ensembl ID		ENSG00000159167
Uniprot IDs		P52823
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Endothelial Cell Migration Muscle Tissue Development Striated Muscle Tissue Development Epithelium Development Regulation Of Endothelial Cell Migration Regulation Of Blood Vessel Endothelial Cell Migration MAML1-RBP-Jkappa- ICN1 Complex Apoptotic Process Involved In Embryonic Digit Morphogenesis Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Vasculogenesis Involved In Coronary Vascular Morphogenesis Venous Endothelial Cell Differentiation Negative Regulation Of Inner Ear Auditory Receptor Cell Differentiation Distal Tubule Development Auditory Receptor Cell Fate Commitment Notch Signaling Involved In Heart Development Regulation Of Aorta Morphogenesis Growth Involved In Heart Morphogenesis Negative Regulation Of Lymphoid Progenitor Cell Differentiation Negative Regulation Of Inner Ear Receptor Cell Differentiation Epidermal Cell Fate Specification Endocardium Morphogenesis Coronary Sinus Valve Morphogenesis Retinal Cone Cell Differentiation Negative Regulation Of Cell Proliferation Involved In Heart Morphogenesis Negative Regulation Of Pro-B Cell Differentiation Cardiac Right Ventricle Formation Glomerular Mesangial Cell Development Cell Migration Involved In Endocardial Cushion Formation Chemical Synaptic Transmission, Postsynaptic Foregut Morphogenesis Compartment Pattern Specification Mitral Valve Formation Arterial Endothelial Cell Differentiation Cellular Response To Tumor Cell Regulation Of Cell Adhesion Involved In Heart Morphogenesis Cardiac Vascular Smooth Muscle Cell Development Negative Regulation Of Extracellular Matrix Constituent Secretion Positive Regulation Of Aorta Morphogenesis Coronary Vein Morphogenesis Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Cardiac Right Atrium Morphogenesis S-adenosylmethionine Biosynthetic Process Methionine Adenosyltransferase Regulator Activity Methionine Adenosyltransferase Complex Somite Specification Cell Surface Receptor Signaling Pathway Involved In Heart Development
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