SSR3

Name	signal sequence receptor subunit 3
Structure
Novel Interactors	1 novel interactors: ERBB3
Interactors	5 interactors: AQP2 PDE4B PRRC2A RABAC1 SSR4
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane
Pathways	SRP-dependent cotranslational protein targeting to membrane
GWAS	Asthma (adult onset) ( 30929738 ) Chronotype ( 30696823 ) Malaria ( 31844061 ) Metabolite levels ( 23823483 ) Testicular germ cell tumor ( 28604732 )
Entrez ID	6747
HPRD ID	16206
Ensembl ID	ENSG00000114850
Uniprot IDs	C9J365 Q9UNL2
PDB IDs	8B6L
GO Terms Enriched among Interactors ?	Lumenal Side Of Membrane Polyol Transmembrane Transport Renal Water Transport Response To Water Deprivation Glycerol Transmembrane Transport Water Transmembrane Transporter Activity Cellular Response To Mercury Ion Metanephric Collecting Duct Development Cellular Response To Water Deprivation Glycerol Transmembrane Transporter Activity Response To Mercury Ion Basolateral Plasma Membrane Positive Regulation Of Cardiac Muscle Tissue Development ErbB-3 Class Receptor Binding ERBB3:ERBB2 Complex Neuregulin Receptor Activity ERBB2-ERBB3 Signaling Pathway Schwann Cell Differentiation ERBB3 Signaling Pathway Neuregulin Binding Regulation Of Cardiac Muscle Tissue Development Neutrophil Homeostasis Synaptic Vesicle Negative Regulation Of Relaxation Of Muscle CAMP Catabolic Process Negative Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Negative Regulation Of Relaxation Of Cardiac Muscle Regulation Of Relaxation Of Cardiac Muscle Sec61 Translocon Complex Response To Water Negative Regulation Of Motor Neuron Apoptotic Process Gamma-tubulin Complex Membrane Collecting Duct Development Endocardial Cushion Development Cellular Response To Epinephrine Stimulus Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Water Channel Activity Regulation Of Motor Neuron Apoptotic Process Motor Neuron Apoptotic Process Cyclic Nucleotide Catabolic Process Response To Epinephrine Protein Tyrosine Kinase Activator Activity Regulation Of Relaxation Of Muscle Apical Plasma Membrane Renal Water Homeostasis Plasma Membrane Schwann Cell Development Positive Regulation Of Calcineurin-NFAT Signaling Cascade 3',5'-cyclic-AMP Phosphodiesterase Activity